Diagnosis of myasthenia
Myasthenia patients usually have muscle weakness, fatigue, eyelid ptosis and other symptoms, so a series of diagnoses are needed to diagnose myasthenia. First, the doctor will preliminarily judge whether there is the possibility of muscle weakness through medical history inquiry and physical examination. Secondly, routine laboratory tests such as blood biochemistry and ethylamine iodine negative conversion test can help screen out the possibility of myasthenia.
However, the most accurate and important diagnostic method is the determination of serum anti acetylcholine receptor antibody (AChR Ab). The level of antibodies in patients with myasthenia is high, and the positive rate of AChR Ab can be detected to confirm myasthenia. If AChR Ab is negative, it is necessary to further check other antibodies, such as muscle nail antibody (MuSK) and low-density Lipoprotein receptor related protein 4 (LRP4) antibody, to exclude the possibility of other autoimmune muscle diseases.
In addition, auxiliary examinations such as electromyography (EMG) and single photon emission computed tomography (SPECT) can also be performed to evaluate the electrical activity of muscles or observe the activity of neuromuscular junction. These findings can help determine the type and severity of myasthenia and provide guidance for treatment.
Treatment of myasthenia
The treatment of myasthenia is mainly divided into symptomatic treatment and immunomodulation treatment. Symptomatic treatment mainly aims at alleviating symptoms, including the use of anticholinesterase drugs, such as acetylcholinesterase inhibitors, to increase neuromuscular conduction and improve muscle strength. Such drugs, such as neostigmine and morphine ammonium bromide, can reduce muscle weakness and fatigue, and improve the quality of life of patients.
Immunomodulation therapy is to reduce the production of autoantibodies by inhibiting the activity of the immune system, thus alleviating the symptoms of myasthenia. Common treatment methods include the use of immunosuppressants such as glutathione, cyclosporine, cyclophosphamide, and corticosteroids. These drugs need to be guided and monitored by doctors to ensure the safety and effectiveness of treatment.
Surgical treatment can also be considered for some patients with serious conditions or ineffective drug treatment. Surgical treatment mainly includes thymectomy and plasma exchange. Thymectomy can reduce the production of autoantibodies and alleviate the symptoms of myasthenia. Plasma exchange can reduce the symptoms of patients with myasthenia by eliminating autoantibodies in the body.
Advantages of myasthenia ophthalmic hospital
As a specialized hospital, Wuhan Myasthenia Eye Hospital has first-class equipment and professional medical team to provide high-quality diagnosis and treatment services for myasthenia patients. First of all, the hospital has advanced EMG and SPECT and other auxiliary diagnostic equipment, which can accurately assess the condition of patients with myasthenia. Secondly, the hospital has rich clinical experience and professional medical staff, who can make individualized treatment plans for different types and severity of myasthenia.
In addition, the hospital also pays attention to the rehabilitation and quality of life improvement of patients, provides comprehensive services such as rehabilitation treatment and psychological support, and comprehensively pays attention to the physical and mental health of patients. The hospital also actively participates in scientific research and academic exchanges, constantly promotes the diagnosis and treatment of myasthenia, and provides better medical security for patients.
Summary
Wuhan Myasthenia Eye Hospital can accurately diagnose myasthenia through a series of diagnostic methods, such as medical history inquiry, laboratory tests and antibody testing. In terms of treatment, the hospital adopts a combination of symptomatic treatment and immunomodulation treatment to provide individualized treatment scheme. In addition, the hospital has advanced equipment and a professional medical team, which actively pays attention to the rehabilitation and quality of life of patients and provides comprehensive medical security for patients with myasthenia.
