The Influence of Aging Fertility on Embryos
Elderly childbearing refers to the pregnancy and childbirth of women over 35 years old. In recent years, with the development of society and the improvement of medical conditions, more and more women choose to be pregnant at an advanced age. However, the aging fertility will bring some potential effects on embryonic development. This article will elaborate on the influence of aging fertility on embryos from four aspects: embryo quality, genetic variation, disease risk and physiological status.
Embryo quality
The growth of female age often leads to the decline of egg quality, which also directly affects the quality of embryos. Studies have found that the eggs of older women are prone to chromosomal abnormalities, which may lead to problems in embryonic development. Chromosomes with abnormal number and structure of chromosomes have a significant impact on the normal development of embryos, which is likely to increase the risk of embryo termination, stillbirth or abortion. In addition, the increase in female age may also lead to a decline in the quality of eggs, making it difficult for fertilized eggs to develop normally, affecting the health of embryos.
In addition, the uterus environment of elderly women may also be affected by age and change, thus affecting the implantation and development of embryos. The changes of endometrial thickness, blood fluidity, nutrient supply and other factors may have adverse effects on embryonic development.
Therefore, women who have given birth at an advanced age need to pay special attention to embryo quality, and reduce the risk of abnormal embryo development through more stringent screening and monitoring measures.
genetic variation
Older childbearing will increase the risk of embryo chromosome abnormalities, which will lead to a series of genetic variation problems. Chromosome abnormalities in eggs often lead to sub micro IQ reduction in embryos, chromosome abnormalities related diseases and other problems. For example, women over 35 years of age are 20 times more likely to have Down syndrome than women under 30 years of age. Therefore, pregnant women who have given birth at an advanced age should know their own and family history of genetic diseases, carry out genetic counseling and genetic testing, so as to do a good job of genetic screening and diagnosis of embryos as soon as possible.
In addition, the risk of some other genetic diseases will also increase for older babies, such as cleft lip and palate, heart disease, etc. These genetic diseases will not only affect the normal growth and development of embryos and infants, but also bring heavy psychological and economic burdens to families.
Risk of illness
As women grow older, the risk of some diseases during pregnancy will also increase. For example, women who give birth at an advanced age are more likely to suffer from pregnancy complications such as gestational diabetes mellitus and pregnancy induced hypertension. These diseases will have adverse effects on embryonic development and maternal health.
In addition, women who give birth at an advanced age are more likely to suffer from some diseases during pregnancy, such as placental abruption, placental implantation, placenta previa, etc. These diseases not only affect the health of pregnant women, but also affect the development of embryos and maternal pregnancy results.
Physiological condition
The function of each system and organ of the body of the elderly women who have children will decline due to the growth of age. For example, the decline of ovarian function will lead to the decline of egg quality, and the blood supply of the uterus and the thickness of the endometrium will also change. The changes of these physiological conditions will directly affect the development of the embryo and the pregnancy results of the mother.
In addition, women who have given birth at an advanced age are more likely to suffer from some age-related diseases, such as osteoporosis, cardiovascular and cerebrovascular diseases, etc. These diseases will increase the risk during pregnancy and indirectly affect the healthy development of embryos.
Summary
The impact of aging on embryos is mainly reflected in the decline of embryo quality, the increase of genetic variation, the increase of disease risk and the decline of physiological status. These effects are mainly related to the growth of women's age. With the growth of women's age, the healthy development of embryos will face more risks. Therefore, women who have given birth at an advanced age need to pay more attention to their own physical conditions and embryo health, and actively take corresponding strategies and measures to ensure the normal development and health of embryos. At the same time, the progress of medical science and technology can also bring more support and help to the elderly childbearing, and improve the probability of embryo health.
