Does the elder male childbearing increase the risk of children's disease?

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The risk of children's diseases caused by male elderly childbearing

With the development of society, more and more men choose to postpone childbearing to a higher age. However, it has aroused widespread concern whether the elderly male childbearing will increase the risk of children suffering from diseases. This article will discuss whether the elderly male fertility will increase the risk of children's disease from the aspects of genetic mutation, sperm quality, disease incidence and children's behavior.

Genetic mutation

There is a certain correlation between male aging fertility and genetic mutation. With the increase of age, the frequency of chromosome abnormalities in sperm gradually increases. Research shows that the probability of genetic mutation of fathers under 35 years old is about 1%, while that of fathers over 40 years old has increased to more than 5%. These genetic mutations may cause children to suffer from diseases related to chromosome abnormalities, such as Down syndrome and congenital stupidity. Therefore, the elderly male childbearing may increase the risk of children suffering from diseases.

In addition, there is also an association between older male fertility and an increased risk of autism associated with chromosomal abnormalities. A study found that children whose fathers are over 40 years old are six times more likely to suffer from autism than children whose fathers are under 30 years old.

Sperm quality

Older men who give birth may also affect sperm quality, thus increasing the risk of children suffering from diseases. With the increase of age, the sperm quality of men will gradually decline. The study found that the degree of DNA damage in the sperm of the elderly father was higher, the sperm concentration and vitality were lower, and the rate of morphological abnormalities was higher. These factors may lead to physical defects and health problems in children, such as congenital heart disease and neurodevelopmental disorders.

In addition, there is a certain correlation between the male elderly childbearing and the children suffering from cataract, premature aging and other diseases. A study found that the risk of cataracts in children born to older men was three times that of children born to fathers of the same age.

Disease incidence

The elderly childbearing of men is also related to the increased incidence of certain diseases. Research shows that children born to older men are more likely to suffer from early onset breast cancer and prostate cancer. In addition, children born to older men may also face an increased risk of chronic diseases such as hypertension, diabetes and cardiovascular disease.

Child behavior

Male elder childbearing may also have a certain impact on children's behavior. A study found that children whose fathers are over 45 years old are more likely to have psychological problems such as anxiety, depression and inattention. In addition, children born to older men are also more likely to show extroverted behavior and social difficulties, which may be related to their father's age.

To sum up, the elderly male childbearing does increase the risk of children suffering from diseases. Studies on genetic mutation, sperm quality, disease incidence and children's behavior all support this conclusion. Therefore, it is suggested that men should consider the impact of age on children's health when choosing to have children, so as to make more intelligent decisions.