How to judge whether IVF fails?
Test tube baby technology plays an important role in the field of modern medicine, which has brought fertility hope to those infertile couples. However, IVF is not always successful, and sometimes faces the possibility of failure. Therefore, before diagnosing whether IVF is a failure, we need to clearly define how to define the success and failure of IVF, as well as the accurate indicators of failure. This article will discuss how to judge the failure of IVF from four aspects: embryo implantation, biochemical pregnancy indicators, embryonic development and evaluation by experienced doctors.
Embryo implantation
Embryo implantation is one of the key steps for the success of IVF. If the selected embryo cannot be implanted in the uterus, the success rate of IVF is significantly lower. Usually, doctors will conduct blood tests 14 days after embryo implantation, which can provide preliminary information about pregnancy. If the pregnancy index is lower than the normal range, or there is no sign of pregnancy, it can be preliminarily determined that IVF may fail.
Furthermore, if the ultrasound examination in the uterus does not find the heartbeat of the implanted embryo, or there is no embryo, then the IVF is likely to fail. This is also one of the indicators that need to be further considered for the re operation of IVF.
However, sometimes after embryo implantation, bleeding or other complications occur, and the test results may not be accurate. Therefore, we also need to consider other indicators to comprehensively judge whether IVF fails.
Biochemical pregnancy indicators
Biochemical pregnancy index is one of the important indicators to measure the success of IVF. About 14 days after embryo implantation, doctors will measure the levels of progesterone and human chorionic gonadotropin (HCG) in the blood. Progesterone is a kind of luteinizing hormone, which will gradually increase in early pregnancy. If the progesterone level is low, it may mean that the luteal function is insufficient, which may lead to the failure of IVF. HCG is a pregnancy hormone. If the level of HCG does not rise or falls within a few days, it may mean that IVF fails.
Although these biochemical indicators are not absolutely reliable criteria, they can be used as a reference for preliminary evaluation of the success of IVF. If biochemical pregnancy indicators are abnormal, further observation of embryonic development is required.
Embryo development
Embryo development is one of the important indicators to judge whether IVF fails. After implantation, doctors usually conduct regular ultrasound examinations to observe the development of the embryo. If the embryo does not develop at the expected speed, or there are obvious abnormalities, it is likely to be one of the signals of IVF failure.
In addition, the chromosome combination test of immature or abnormally developed embryos can detect whether there are chromosome abnormalities in the embryos, such as chromosome deletion, selective deletion, etc. These are all possible reasons for IVF failure.
Evaluation by experienced doctors
In addition to the above indicators, the observation and evaluation of experienced doctors are equally important. Whether it is embryo implantation, biochemical pregnancy indicators or embryo development, experienced doctors are required to make judgments and assessments. Doctors will comprehensively consider multiple factors, including the patient's age, patient's physical condition, embryo quality, etc., to judge the success of IVF.
To sum up, judging whether IVF fails requires comprehensive consideration from multiple aspects. Embryo implantation, biochemical pregnancy indicators, embryo development and evaluation by experienced doctors are important judgment indicators. When there are obvious abnormalities in these indicators, we can preliminarily judge that IVF may fail. However, the final judgment still needs rich clinical experience and comprehensive evaluation of professional doctors.
