Causes of IVF Multiple Failures
IVF is an assisted reproductive technology, which is an important reproductive choice for couples who cannot conceive naturally. Although the IVF technology has developed rapidly in recent decades, and many successful cases have been achieved, some couples are faced with the problem of multiple failures of IVF. The following will elaborate on the reasons for the failure of IVF from the aspects of embryo quality, hormone level, intrauterine environment and diet.
Embryo quality
Embryo quality is one of the important factors affecting the success rate of IVF. In the process of embryo culture, the shape and number of embryos and the normality of chromosomes will affect the success rate. First of all, the morphology of the embryo needs to meet the normal development standards, with good cell division and proliferation. Secondly, the normality of chromosomes is also crucial to the development and implantation ability of embryos. Therefore, it is necessary to carry out chromosome screening for embryos before transplantation. If the embryo quality is poor, it may lead to the failure of IVF.
In addition, poor quality embryos may also be related to the patient's age and constitution. For older women, the quality of eggs may decline, which will increase the probability of IVF failure. In addition, women with endometriosis or endometrial polyps and other diseases may not have an appropriate uterine environment for embryo implantation, which will also increase the failure rate of IVF.
Hormone levels
Hormone level is one of the key factors for the success of IVF. In the process of IVF, the application of hormone is very important. It can regulate follicular development and ovarian function, and promote the maturation and release of eggs. However, in hormone therapy, the choice of dose and use time needs to be very accurate. The success rate of IVF will be affected if the hormone is too high or insufficient.
In addition, some individual differences may also lead to changes in hormone levels, thereby affecting the results of IVF. Some couples may be highly sensitive to hormones and prone to side effects, such as ovarian hyperstimulation syndrome, endometrial weakness, etc., which may lead to the failure of IVF.
Intrauterine environment
The intrauterine environment has an important impact on the development and implantation of IVF. Some factors may lead to unsuitable intrauterine environment, which may lead to IVF failure. Endometriosis, hysteromyoma, endometrial polyps and other diseases will lead to changes in the internal environment of the uterus and affect the implantation force of the embryo. In addition, problems such as abnormal uterine morphology and loose cervix can also lead to the failure of IVF.
The intrauterine environment may also be affected by infection and other factors. For example, bacterial infection, endometritis, etc. will lead to changes in the uterine environment, thus affecting the implantation and development of embryos.
diet
Diet also has a greater impact on the success of IVF. A balanced diet can improve the quality of eggs and embryos, and promote the development and implantation of embryos. Some studies also found that some specific foods and nutrients can help to increase the success rate of IVF infants, such as foods rich in folic acid, foods rich in vitamin B6 and B12, etc.
However, poor diet habits may lead to underweight or overweight, thus affecting the development of rich follicles and ovarian function. In addition, excessive intake of caffeine, tobacco, alcohol and other substances will also have a negative impact on the success of IVF.
Summary
The reasons for many failures of IVF involve embryo quality, hormone level, intrauterine environment and diet. The difference in embryo quality, imbalance in hormone levels, discomfort in the intrauterine environment and poor diet habits may lead to the failure of IVF. Therefore, before IVF, we should fully understand our own situation, select appropriate hospitals and clinical teams, and pay attention to adjusting our living habits and diet to improve the success rate of IVF.
