Requirements of IVF on sperm quality
IVF is a kind of assisted reproduction technology. Through laboratory operation, the sperm and eggs are cultured for in vitro fertilization, and then the fertilized eggs are implanted into the uterus of women for pregnancy. Sperm quality is critical to the success rate of IVF and the healthy development of infants. The requirements of IVF for sperm quality are described in detail in terms of sperm vitality, sperm morphology, sperm concentration and DNA integrity.
Sperm motility
Sperm vitality refers to the motility and survival rate of sperm. High quality sperm should have high vitality and be able to swim quickly and forcefully so as to reach the egg and complete fertilization smoothly. If the sperm vitality is low, the success rate of fertilization will be greatly reduced. Therefore, sperm motility is a very important indicator for IVF.
The traditional observation method is to observe the sperm movement under the microscope and classify them. However, with the development of modern medical science and technology, we can use computer aided system to evaluate sperm motility more accurately. Through this system, we can analyze and measure the speed, trajectory and swimming ability of sperm, so as to better evaluate the quality of sperm.
The research of the well-known XXXX hospital found that sperm motility has an important impact on the success rate of IVF. They found that patients with high sperm motility were more likely to successfully conceive and had better embryo quality. Therefore, improving sperm motility is a key link to improve the success rate of IVF.
Sperm morphology
Sperm morphology refers to the appearance, shape and structure of sperm. Normal mature sperm should have complete morphology and structure, the head should be oval, and the neck and tail should be clearly visible. If sperm morphology is abnormal, such as shortened neck, deformed head, etc., it will affect its ability to penetrate the egg, thus affecting the fertilization rate of IVF.
Modern medical technology can use high-power microscope and electron microscope to accurately evaluate the morphology of sperm. Studies have shown that there is a significant correlation between sperm morphological abnormalities and the reduction of fertilization rate and the increase of embryo abnormalities. Therefore, in the process of selecting sperm for IVF, normal sperm should be one of the first criteria to be considered.
A study conducted by the famous XXXX Hospital in the United States found that when sperm with abnormal morphology is mixed with sperm with normal morphology, the fertilization rate decreases significantly. Therefore, in the process of IVF, selecting sperm with normal morphology can effectively improve the fertilization rate and embryo quality.
Sperm concentration
Sperm concentration refers to the number of sperm per unit volume, usually measured by the number of sperm per milliliter. Normal sperm concentration should be 15-200 million/ml. Too low sperm concentration may lead to insufficient sperm quantity, thus affecting the success rate of fertilization.
In the process of IVF, patients with low sperm concentration usually need to extract sperm and use special methods to obtain enough sperm for fertilization. The common method is sperm granule injection (ICSI). The success rate of IVF can be improved by selecting sperm with high concentration for fertilization.
The research of XXXX Hospital found that sperm concentration was positively correlated with fertilization rate. They observed that patients with higher sperm concentrations were more likely to have successful pregnancies. Therefore, in the process of IVF, selecting samples with high sperm concentration can increase the success rate of fertilization.
Sperm DNA integrity
Sperm DNA integrity refers to the integrity of genetic material DNA in sperm. The integrity of sperm DNA plays an important role in the success rate of IVF and the healthy development of infants. Studies have shown that sperm DNA damage can lead to abnormal embryonic development, early embryo termination or abortion and other adverse results.
With the development of modern medical science and technology, we can evaluate the integrity of sperm DNA by microscopy and staining techniques. The integrity of sperm DNA can be effectively judged by evaluating DNA breaks, chromosome abnormalities and other indicators.
Some studies have found that the integrity of sperm DNA is closely related to the clinical results of IVF. Patients with high sperm DNA integrity are more likely to be successful in pregnancy, and the embryo quality is better. Therefore, in the process of IVF, selecting samples with high sperm DNA integrity can improve the healthy development rate of infants.
Summary
IVF has strict requirements on sperm quality, including sperm motility, sperm morphology, sperm concentration and sperm DNA integrity. High quality sperm can improve the success rate of IVF and the healthy development of infants. Therefore, in the process of IVF, doctors will conduct detailed evaluation and screening of sperm samples to ensure that the sperm quality meets the requirements.
