What is the correlation between the follicle size of IVF and?
IVF is an assisted reproductive technology that can help couples who cannot conceive naturally realize their reproductive dreams. In IVF, the size of follicles plays an important role in the success rate. This article will elaborate on four aspects: female age, ovarian reserve function, choice of intervention and control drugs and ovarian stimulators from the perspective of follicle size affected.
1. Female age
Female age is an important factor affecting the size of IVF follicles. With the growth of age, women's ovarian function will gradually decline, and the quality of eggs will also decline. Therefore, older women may produce smaller follicles, and the number of follicles will decrease. Research shows that the size and number of follicles produced by women under 30 years old are relatively good, while those produced by women over 35 years old will be significantly reduced.
The influence of female age on follicle size is mainly due to changes in ovarian function. With the increase of age, the number of primordial follicles in women's ovaries will gradually decrease, and the quality and development ability of follicles will also decline. Therefore, young women will produce more and moderately sized follicles in the process of IVF, thus improving the possibility of successful pregnancy.
Although women's age has a certain impact on the size of follicles, the development of IVF technology allows older women to still have a chance to successfully conceive. Hospitals use higher doses of ovarian stimulators to increase the number of follicles, thereby improving the chance of pregnancy.
2. Ovarian reserve function
Ovarian reserve function refers to how many primordial follicles remain in the female ovary. The size and number of follicles are closely related to the ovarian reserve function. The number of primordial follicles in the female ovary can be known through blood sampling test. Generally speaking, the more abundant the ovarian reserve, the better the number and size of follicles produced by women.
Ovarian reserve function is affected by many factors, including women's age, reproductive system diseases, radiation exposure, etc. The older a woman is, the lower the number and quality of follicles will be, and the ovarian reserve function will be weakened accordingly. However, women with ovarian diseases or who have received radiotherapy, chemotherapy and other treatments will also suffer from damage to ovarian reserve function to some extent.
For women with low ovarian reserve function, hospitals can use higher doses of ovarian stimulators to increase the number and size of follicles. In addition, the selection of ovarian stimulators can also be adjusted according to the ovarian reserve function to improve the success rate of IVF.
3. Intervention and control drugs
In the process of IVF, doctors will formulate intervention and control drug use plans according to women's individual conditions. Intervention and control drugs mainly include ovulation promoting drugs and follicle growth promoting drugs. These drugs can promote the development and maturation of follicles, thus improving the success rate of IVF.
Different intervention and control drugs have different effects on the size of follicles. Ovulation promoting drugs can help follicles develop rapidly and increase the size of follicles. And follicle growth promoting drugs can promote the better development of follicles, thus producing better quality eggs.
The hospital may use different intervention and control drugs according to the specific situation of women. For example, for women with poor ovarian reserve function, doctors may use ovulation promoting drugs to increase the number and size of follicles. For older women, follicle growth promoting drugs and ovulation promoting drugs can be used together to improve the success rate.
4. Selection of ovarian stimulators
The selection of ovarian stimulators is also an important factor affecting the size of IVF follicles. Common ovarian stimulators include human chorionic gonadotropin (HMG) and human chorionic gonadotropin luteinizing hormone (HCG).
HMG can stimulate the growth and development of follicles and promote the formation of eggs. Therefore, women who use HMG may produce larger follicles. HCG is a drug used for ovulation guidance, which can help follicles break down smoothly and release eggs.
The hospital will select appropriate ovarian stimulants according to the specific conditions of women. For example, older women may need to use higher doses of HMG to stimulate follicular development. For women with low ovarian reserve function, HMG and HCG can be used together to increase the number and size of follicles.
Summary
The size of follicles in IVF is closely related to female age, ovarian reserve function, choice of intervention and control drugs and ovarian stimulators. The number and size of follicles produced by young women with good ovarian reserve function are relatively good, and the success rate is relatively high. Intervention and control drugs can promote the development and maturation of follicles, thus improving the success rate of IVF. The hospital will select appropriate ovarian stimulators according to the specific conditions of women to better regulate the development and maturation of follicles.
