Causes of premature birth in test tube infants
In vitro preterm birth refers to the premature birth of babies obtained through assisted reproductive technology (ART) during pregnancy. Preterm birth will have a certain impact on the health and survival rate of infants. The following will elaborate on the causes of IVF preterm delivery from four aspects: health status of pregnant women, intrauterine environment, multiple pregnancy and pregnancy complications.
Health status of pregnant women
The health status of pregnant women is one of the important factors affecting IVF preterm delivery. Some serious chronic diseases, such as hypertension, diabetes and thyroid dysfunction, will increase the risk of premature delivery of IVF. These diseases can cause abnormal changes in maternal hormone levels, affect the stability of the intrauterine environment, and lead to premature delivery of the fetus. In addition, the nutritional status of pregnant women is also related to premature delivery. Malnutrition will lead to fetal hypoplasia and increase the incidence of premature birth of test tube babies.
The lifestyle of pregnant women during pregnancy is also related to preterm delivery. Smoking, drinking, and overwork and stress during pregnancy all increase the risk of premature delivery of IVF babies. These unhealthy lifestyles will have a negative impact on the health of pregnant women, which will increase the incidence of premature delivery.
Intrauterine environment
The intrauterine environment plays an important role in IVF preterm delivery. Cervical incompetence means that the cervix lacks sufficient strength and tension to sustain pregnancy to term. This situation is very common in IVF pregnancy, which may be caused by the damage to the cervical structure caused by assisted reproductive technology.
Endometriosis is another factor that may lead to premature delivery of IVF. Endometriosis is the growth of endometrial cells outside the uterus, often leading to inflammation and fibrosis of the endometrium. Abnormal endometrium will lead to increased uterine contraction during pregnancy, increasing the risk of premature delivery.
Multiple pregnancy
IVF usually chooses to implant multiple embryos in assisted reproductive technology, which increases the risk of multiple pregnancies. Multiple pregnancy is a high-risk pregnancy, which will significantly increase the risk of premature delivery of test tube babies. Multiple pregnancy will increase the burden and risk of the uterus, making the uterus contract prematurely, thus leading to premature delivery.
In addition, multiple pregnancies also increase the risk of placental insufficiency. Placental insufficiency will lead to fetal dysplasia in the uterus, increasing the risk of premature delivery.
Pregnancy complications
Pregnancy complications are also one of the reasons for IVF preterm birth. Hypertension during pregnancy and pre eclampsia are two common complications of pregnancy, which will increase the risk of premature delivery. These complications will lead to vasoconstriction and capillary damage in pregnant women, and then affect the supply of oxygen and nutrition to the fetus.
Pregnant women may also suffer from other diseases during pregnancy, such as infection and intracranial infection. These diseases will have a negative impact on the development of the fetus and increase the incidence of premature birth of test tube babies.
Summary
Preterm birth in vitro is a common complication of assisted reproductive technology. The health status of pregnant women, intrauterine environment, multiple pregnancy and pregnancy complications are the main causes of IVF preterm delivery. In order to reduce the risk of premature delivery, pregnant women need to maintain good health, avoid bad lifestyles, and conduct regular medical examinations. In addition, reasonable embryo transfer policy and active prevention of pregnancy complications are also the key to reduce the risk of premature delivery.
