Contraindications of IVF
IVF is an assisted reproductive technology. Through in vitro fertilization and embryo transfer, couples who cannot conceive naturally can realize their reproductive dreams. However, not all couples are suitable for IVF because of some contraindications. This article will discuss the contraindications of IVF from four aspects: genetic diseases, maternal health, male infertility and age.
Genetic disease
Some genetic diseases are contraindications to IVF. For example, some autosomal inherited diseases, chromosome abnormalities and specific gene mutations will be regarded as contraindications. This is because in the process of embryo transfer, once the embryo with genetic disease is selected, it will bring trouble and pain to the child's future life. Therefore, before IVF, couples need to receive genetic counseling and genetic testing to know whether they have genetic diseases, so as to avoid passing these diseases on to the next generation.
In addition, familial onset of some syndromes and genetic diseases is also a contraindication of IVF. For example, couples with a family history of hereditary tumors should carefully consider IVF, because the risk of embryos carrying related gene mutations is high, which is likely to lead to the next generation suffering from the same tumor disease.
Such contraindications require couples to conduct comprehensive genetic testing before IVF, so as to fully understand their own genetic status, and work with doctors to develop appropriate birth plans.
Maternal health
Maternal health is also one of the contraindications of IVF. First, serious organic diseases, such as heart disease and kidney disease, will increase the risk during pregnancy. If pregnant women have these diseases, they may cause serious harm to themselves and the fetus.
Secondly, some gynecological diseases are also contraindications of IVF. For example, hysteromyoma, polycystic ovary syndrome, etc. will affect the quality and implantation ability of eggs, thus affecting the success rate of IVF. Therefore, if one of the couples suffers from serious gynecological diseases, it is recommended to receive treatment and conditioning of related diseases before IVF treatment, so as to improve the success rate of IVF.
In addition, if women suffer from serious abnormal immune system diseases, such as severe autoimmune thyroid disease, it will also affect the success rate of IVF.
Male infertility
Male infertility is another contraindication of IVF. If men suffer from serious sperm quality abnormalities, oligozoospermia, azoospermia and other diseases, which make it impossible to conceive in a natural way, then IVF is a feasible option. However, if men suffer from serious genetic diseases or chromosomal abnormalities, this may become a contraindication for IVF. Therefore, before choosing IVF, men also need to carry out relevant examinations and consultations to assess whether it is suitable for IVF.
Age
Age is an important factor in IVF. The age of women has an important impact on the success rate of IVF. It is generally believed that after the age of 35, the quality of eggs begins to decline, which may lead to the decline of fertility. Therefore, women over 40 years old are often considered as contraindications to IVF. Similarly, the age of men will also affect the quality and quantity of sperm, thus affecting the success rate of pregnancy.
To sum up, IVF has some contraindications, including genetic diseases, maternal health, male infertility, age and other factors. Couples should receive comprehensive genetic counseling and genetic testing before choosing test tube babies to understand their own genetic status; At the same time, couples with organic diseases, gynecological diseases and male infertility should receive treatment and conditioning of related diseases before IVF treatment; Finally, the age of the couple is also an important consideration. Choosing the right age for IVF can improve the success rate and reduce complications.
