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What is the role of IVF pretreatment?



Effects of Pretreatment on IVF

Pretreatment of IVF is an important step in assisted reproductive technology. Through the detection and screening of embryos, healthy embryos can be selected before transplantation to improve the success rate of IVF and reduce the transmission of genetic diseases. The role of IVF pretreatment will be elaborated from four aspects.

 What is the role of IVF pretreatment?

Genetic disease screening

The primary goal of IVF pretreatment is to screen embryos for genetic diseases. Embryos obtained by artificial fertilization or in vitro fertilization technology shall be subject to gene detection during the culture process to screen embryos with severe genetic disease genes at an early stage, so as to avoid transferring such embryos to the mother. For couples carrying genetic disease genes, this means reducing the risk of passing diseases on to the next generation and increasing the probability of healthy babies.

Taking Peking Union Medical College Hospital as an example, their IVF pretreatment center is equipped with the most advanced genetic diagnostic equipment in China, which can detect all common genetic diseases, including thalassemia, cystic fibrosis, etc. The center can carry out rapid and accurate genetic disease screening at the early stage of embryo growth, providing strong support for couples to select healthy embryos.

Chromosome abnormality detection

Chromosome abnormality is one of the main causes of infertility and habitual abortion. Test tube baby pretreatment can screen out normal embryos by detecting chromosome abnormalities of embryos, improve the success rate of pregnancy and reduce the risk of abortion. Chromosome abnormality detection is mainly carried out through preoperative gene diagnosis technology, combined with the process of egg taking, fertilization and culture of embryos, to exclude embryos with chromosome abnormalities.

Ruijin Hospital affiliated to Shanghai Jiaotong University is one of the first hospitals in China to carry out assisted reproductive technology. They introduced the latest chromosome screening technology in the IVF pretreatment center, which can detect embryos throughout the process, effectively reducing the rate of pregnancy failure and fetal abnormalities caused by chromosomal abnormalities.

Gender Screening

Under certain circumstances, couples may want to choose the sex of their baby because of family genetic diseases or other reasons. Pretreatment of IVF provides the possibility of sex screening. Through in vitro fertilization, the obtained embryos can be sex screened and then transferred into the mother. This technology has to some extent met the expectations of some families for the baby's gender.

Take Guangzhou Nanfang Women and Children's Hospital as an example. Their IVF pretreatment center provides gender screening services. The center has a professional technical team and advanced equipment, which can accurately determine the sex of embryos. However, it should be noted that gender screening is limited in some countries and regions, and relevant laws and regulations need to be observed.

Improve the success rate of IVF

The role of IVF pretreatment also includes improving the success rate of IVF. Through fine screening and testing of embryos, selecting healthy embryos for transplantation can improve the success rate of transplantation and pregnancy rate, reduce the number of repeated operations, and thus reduce the physical and psychological burden of couples. In addition, pretreatment can also help doctors better understand the fertility of patients and develop more accurate treatment plans.

Summary

In vitro baby pretreatment plays an important role in assisted reproductive technology. It provides couples with the opportunity to screen healthy embryos, reduce the transmission of genetic diseases, reduce the risk of abortion caused by chromosomal abnormalities, and meet some families' expectations for the baby's gender. At the same time, pretreatment can also improve the success rate of IVF and reduce the psychological and physical burden of couples. With the continuous progress of technology and the continuous development of hospitals, IVF pretreatment will provide more possibilities for more and more couples to realize their reproductive dreams.

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