Why is the success rate of older IVF low?
IVF is an assisted reproductive technology, which aims to help couples who are difficult to conceive naturally realize their reproductive aspirations. However, the success rate of IVF is often low in older cases. This article will elaborate on the reasons for the low success rate of older IVF from the aspects of physiology, biochemistry, psychology and technology.
1、 Physiological cause
Age increase will lead to the decline of female ovarian function and egg quality, which is one of the main reasons for the low success rate of older IVF. The risk of chromosomal abnormalities in female eggs increases with age. At the same time, women may have problems such as thinner endometrium and reduced blood supply due to their age, which reduces the chances of implantation of fertilized eggs.
In addition, male reproductive function will also decline. With the increase of age, the semen quality, sperm quantity and vitality of men gradually decrease, which has a negative impact on the success rate of egg fertilization during IVF.
To sum up, these physiological changes make older couples face more difficulties in IVF, which leads to a low success rate.
2、 Biochemical cause
Another important reason for the low success rate of older IVF infants is the change of hormone levels. As women grow older, their ovarian function weakens, leading to follicular dysplasia and ovulation problems, which affects their chances of pregnancy. In addition, changes in estrogen and luteinizing hormone levels in women's blood will also have a negative impact on follicular development and fertilization during IVF.
For males, the sperm quality of older males may be affected by the decline of testicular tissue function, thus reducing the success rate of IVF.
These biochemical changes may cause older couples to encounter more difficulties in IVF, thus reducing the success rate.
3、 Psychological causes
Test tube baby is a process that challenges couples' psychological endurance. The long-term treatment process, repeated failures and uncertain results will have a huge impact on the couple's psychology. Older couples may feel more pressure and anxiety, which not only affects cooperation and confidence in the treatment process, but also may affect their physical status, further reducing the success rate.
In addition, psychological factors may also lead to abnormal changes in physical functions, such as stress and tension during pregnancy may affect the growth and development of the fetus.
Therefore, the importance of mental health cannot be ignored. Older couples need to pay full attention to and manage their own mental state in the process of IVF.
4、 Technical reasons
The low success rate of older IVF infants is also related to technical factors. IVF technology requires doctors' experience and practice, and the operation of each link needs to be accurate. If the technology is operated improperly, such as poor embryo culture, fertilization process problems, etc., it will lead to IVF failure.
In addition, older couples may need to experience multiple IVF cycles to successfully conceive, and multiple attempts may increase the chance of technical errors and further reduce the success rate.
Therefore, in older IVF infants, the technical level and experience of doctors are very important. Improving the accuracy and success rate of technical operations is the key to improving the success rate of older IVF infants.
To sum up, the low success rate of older IVF infants can be attributed to many aspects such as physiology, biochemistry, psychology and technology. These reasons include age-related physiological changes, changes in hormone levels, psychological pressure and dependence on technology. Therefore, older couples need to take these factors into full consideration when carrying out IVF, and actively seek professional guidance and support from doctors to increase the success rate of IVF.
