Analysis of the Causes of IVF Failure
IVF is an assisted reproductive technology. Through taking eggs, fertilizing and cultivating sperm in the laboratory, and finally implanting the fertilized eggs into the uterus of pregnant women, IVF can help couples who cannot conceive naturally realize their reproductive dreams. However, IVF is not omnipotent, and there is a certain risk of failure. The following will discuss the reasons for IVF failure from the aspects of embryo quality, age, implantation technology and psychological factors.
Embryo quality problems
The success of IVF is closely related to embryo quality. First, during in vitro fertilization, the quality of fertilized eggs may be affected. Some fertilized eggs develop slowly, while others develop abnormally, which will reduce the possibility of successful embryo implantation. Secondly, whether a good training environment can be provided in the training process is also a key factor. If the culture environment is poor, or the culture time is too long, it may lead to chromosome abnormalities or dysplasia of embryos, which will lead to failure of IVF.
In addition, artificial manipulation during in vitro fertilization may also affect embryo quality. The technical requirements for egg retrieval and sperm injection are very high, and careless operation may have adverse effects on embryo quality. In addition, if there is no genetic testing of the embryo in the process of embryo selection, it may lead to implantation of embryos with chromosome abnormalities, thus increasing the risk of IVF failure.
Age factor
Female age is also one of the important factors affecting the risk of IVF failure. The female reproductive system and egg quality gradually decline with the increase of age. After the age of 35, the female fertility will decline significantly. Therefore, the older women are, the lower the success rate of IVF will be.
In addition, the age of men is also related to the success rate of IVF. As men grow older, the quality and quantity of sperm may decline, thus affecting the fertilization process. Therefore, the age of both spouses may have an impact on the results of IVF.
Implantation technical problems
The success of IVF is also affected by implantation technology. In the process of implantation, doctors need to accurately determine the optimal implantation time and location to increase the success rate of embryo implantation. If the implantation time is not accurate or the implantation position is selected improperly, the embryo may not be successfully implanted, which may lead to the failure of IVF.
In addition, the preparation of endometrium is also a key factor affecting the results of IVF. If the endometrium does not reach the ideal thickness and state, it cannot provide a good implantation environment, thus reducing the success rate of IVF.
psychological factor
Psychological factors may also affect the success rate of IVF. IVF is usually a process full of expectation and pressure for couples. The long-term treatment process and uncertain results may have an impact on the psychological status of the couple, thus affecting the hormone level and immune function in the body, and further affecting the success of IVF.
In conclusion, the failure of IVF can be attributed to embryo quality, age, implantation technology and psychological factors. Relevant hospitals such as Peking Union Medical College Hospital and Ruijin Hospital affiliated to Shanghai Jiaotong University School of Medicine have high professional level and rich experience in the field of IVF, which can provide better IVF pregnancy assistance services for couples.
