Why is IVF possible to fail?
IVF technology is an important breakthrough in modern fertility medicine, which can help couples who cannot conceive naturally achieve their fertility aspirations. However, although this technology has achieved remarkable success in many aspects, the possibility of failure still exists. This article will explain the reasons of IVF failure from embryo selection, implantation process, physical reaction and psychological factors.
Difficulties in embryo selection
In the process of IVF, it is very important to select high-quality embryos. However, it is difficult to select a healthy embryo because the quality of the embryo can not be determined in advance. First, the quality of fertilized eggs may be affected by some genetic defects, chromosome abnormalities or other physiological problems. Therefore, in the process of embryo selection, doctors need to conduct multiple sampling tests to judge the health of embryos, which increases the possibility of failure.
Secondly, the number of embryo transfers will also affect the success rate. Generally, in order to improve the chance of successful pregnancy, doctors will choose to transplant multiple embryos into the uterus, but doing so will also increase the risk of multiple pregnancies. Multiple pregnancy will cause a series of complications, including premature delivery, fetal dysplasia, etc., which further increases the failure rate of IVF.
In addition, because the growth environment of the embryo in the culture dish cannot completely simulate the intrauterine environment, some embryos may develop poorly during the culture process, leading to pregnancy failure. Therefore, the difficulty of embryo selection is an important factor in IVF failure.
Challenges during implantation
The process of IVF implantation is a very critical link. During implantation, doctors need to place the embryo precisely in the endometrium to ensure that the embryo can be implanted smoothly. However, due to factors such as the state of endometrium and the accuracy of implantation technology, the implantation process is not always successful.
First of all, the thickness and quality of endometrium are crucial for embryo implantation. If the thickness of endometrium is not enough or there are abnormal conditions, it is difficult for the embryo to implant on it, thus leading to implantation failure. Secondly, the operational accuracy of implantation technology is also a key factor. The implantation process requires doctors to master certain skills to ensure that the embryo can be placed correctly. Once the operation is improper, the embryo may not be successfully implanted, leading to failure.
In addition, the preparation before implantation is also crucial. For example, women need to go through a series of hormone treatments to promote the growth of endometrium. If these preparations do not meet the standard, the success rate will be reduced. Therefore, various challenges in the implantation process are also one of the reasons for IVF failure.
Influence of body reaction
In the process of IVF, women need to receive a lot of hormone therapy and surgical procedures, which will have an impact on the body. First of all, hormone therapy may cause women to suffer from some side effects, such as mood fluctuations, breast pain, abdominal distension, etc. These discomforts may affect women's physical and mental status, and thus adversely affect the success rate of IVF.
Secondly, the body's response to hormone therapy is unpredictable. Some women may overreact to hormone therapy, leading to ovarian hyperstimulation syndrome (OHSS). OHSS may lead to ovarian swelling, ascites accumulation and other serious consequences, even requiring hospitalization. The uncertainty of these physical responses increases the risk of IVF failure.
Influence of psychological factors
IVF is an important reproductive experience for couples, so psychological factors will also affect its success rate. Psychological pressure, anxiety and emotional fluctuations may interfere with women's hormone balance, thus affecting ovarian function and endometrial growth, and thus affecting the success rate of pregnancy.
In addition, the failure of IVF is a heavy blow to couples, which may lead to further deterioration of their emotions, and even doubt and despair of continuing to try. This accumulation of psychological pressure and negative emotions will further reduce the success rate of IVF.
summary
The possibility of IVF failure lies in embryo selection, implantation process, physical reaction and psychological factors. Difficulties in embryo selection, challenges during implantation, physical reactions and psychological factors will all affect the success rate of IVF. Therefore, before IVF, prospective parents need to fully understand these risks, and communicate and evaluate with doctors in detail to choose their own reproductive mode.
