Why does IVF transplantation lead to non implantation?
IVF is a kind of assisted reproductive technology, which aims to help couples who cannot conceive naturally realize their reproductive dreams. However, it is frustrating that non implantation is one of the common failures in this technology. This article will discuss why IVF transplantation can lead to non implantation from many aspects.
Endometrial problems
Endometrium is one of the key factors for successful implantation. If the endometrium is too thin or abnormal, the embryo cannot be implanted. For example, the endometrium cannot become thick enough due to abnormal hormone levels. In addition, inflammation of endometrium or other pathological problems may also interfere with implantation. Therefore, some patients who failed in IVF transplantation may need to go through more in-depth examination and treatment to solve endometrial problems.
In addition, the quality of embryos is also an important factor in the process of IVF. It is difficult for low-quality embryos to obtain sufficient nutrition and support in the endometrium, so they cannot be successfully implanted. In order to improve the success rate of implantation, doctors usually screen the best embryos for transplantation.
Immunization issues
The immune system plays an important role in regulating the implantation process. Abnormal immune response to embryo and endometrium may lead to implantation failure. Some patients may have diseases with an overactive immune system, such as autoimmune diseases, which will cause the immune system to attack the embryo and prevent its implantation. In addition, the drugs used during transplantation may also interfere with the normal function of the immune system, thus reducing the chance of successful implantation.
Abnormal hormone level
IVF transplantation requires hormone therapy to promote ovarian ovulation and endometrial growth. If the patient's hormone level is abnormal and cannot reach the appropriate level, it will affect the success of implantation. For example, low levels of estrogen in the blood may cause the endometrium to fail to grow and mature enough to prevent the embryo from being implanted. On the contrary, too high a hormone level will also interfere with the growth environment of the endometrium, thus affecting the smooth progress of implantation.
Other factors
In addition to the above factors, there are other factors that may lead to IVF transplantation not being implanted. For example, a patient may have structural abnormalities in the reproductive system, which may affect the embryo's passage through the fallopian tube to the uterus. In addition, factors such as age, weight, diet and lifestyle may also affect the success rate of bed.
In conclusion, there are various reasons for IVF transplantation leading to non implantation. Endometrial problems, immune abnormalities, abnormal hormone levels and other factors may have a negative impact on the process of implantation. Therefore, in order to improve the success rate, doctors need to comprehensively consider the individual situation of patients and take appropriate treatment measures.
