Why does IVF often fail?
The development of IVF technology has brought good news to many infertile couples. However, the success rate of IVF still has a high risk of failure. In order to better understand why IVF often fails, we will elaborate from several aspects below.
1. Physiological factors
The success of IVF often depends on the coordination of multiple physiological factors. First, women's ovaries must function normally and produce enough healthy eggs. However, due to age, illness or other reasons, many women's ovarian function is affected. Secondly, men should have sufficient quantity and quality of sperm to successfully combine with eggs. Also, the female uterus environment should be suitable for embryo implantation and development. In some cases, women may have problems with the uterus that cannot be conceived.
In addition, genes can also affect the failure rate of IVF. Gene mutation of some diseases may lead to abnormal embryonic development, failure of implantation or abortion in early pregnancy.
Finally, the immune system may also have an impact on the success of IVF. Overactivity of the immune system may expel redundant embryos from the body, leading to pregnancy failure.
2. Technical operation factors
The success and failure of IVF technology are also closely related to the operation level of medical institutions and doctors. First of all, the process of egg retrieval requires doctors to have superb technology and experience to accurately obtain eggs. Improper egg extraction may lead to insufficient or poor quality eggs, thus reducing the success rate.
Secondly, the fertilization process needs skilled medical staff to operate to ensure the successful combination of sperm and eggs. If the fertilization process is affected by pollution, unsuitable environment or other factors, the development and survival rate of embryos will be affected.
Finally, in the process of embryo transfer, doctors need to master appropriate time and methods. Choosing the right embryo and implanting it into the uterus accurately is the key to the success of IVF.
3. Psychological factors
The IVF process itself is a journey of great psychological pressure for couples. Anxiety, nervousness, worry and expectation may increase the physical and psychological burden, and thus affect the success of IVF. Research shows that emotional stress is related to physiological changes such as hormone secretion, endometrial thickness and uterine contraction, which may affect embryo implantation and pregnancy.
At the same time, once IVF fails, couples may fall into depression, disappointment and despair. This negative emotion may have a negative impact on the body, thus affecting the success rate of the next IVF.
4. Hidden health problems
Sometimes, the cause of IVF failure may be related to the hidden health problems of a couple or a person. Some diseases or symptoms may not be found by the general physical examination, but will affect the fertility and embryonic development process. For example, recessive health problems such as polycystic ovary syndrome, endocrine disorders, uterine fibroids may lead to the failure of IVF.
In general, there are many reasons for IVF failure. Physiological factors, technical operation factors, psychological factors and hidden health problems may affect the success of IVF. Further scientific research and continuous improvement of technical level will help reduce the failure rate of IVF and bring hope for more infertile couples.
