What is the relationship between folic acid and IVF?
Folic acid is an important B vitamin, which is essential for women's health before and during pregnancy. IVF is an assisted reproductive technology, which is often accompanied by the risk of abortion. This article will elaborate the relationship between folic acid and IVF from several aspects.
Role of folic acid
Folic acid plays an important role in embryonic development and nervous system formation. It can help cells synthesize DNA and RNA, and participate in gene expression regulation. In addition, folic acid can also help protect the spinal column of the fetus and prevent the occurrence of neural tube defects, such as spina bifida. Therefore, folic acid is very important for the healthy growth of IVF.
Although many foods contain folic acid, many women still suffer from folic acid deficiency before and during pregnancy. This is because women's folic acid demand increases during pregnancy, and it is difficult to meet this demand through diet. Therefore, doctors often advise women to start taking folic acid supplements before the start of pregnancy plan to prevent possible folic acid deficiency.
Relationship between Folic Acid and IVF Abortion
IVF is a kind of assisted reproductive technology, which helps infertile couples achieve their reproductive aspirations through artificial fertilization. However, the abortion rate of IVF is relatively high. A study has shown that folic acid supplementation in the IVF diet can reduce the risk of miscarriage.
First, folic acid can affect the implantation ability of embryos. Implantation is the first critical step of embryonic development, which is crucial for the continued development of embryos and successful pregnancy. Folic acid supplementation can promote the healthy development of endometrium, improve the implantation rate of embryos in the uterus, and reduce the risk of abortion.
Secondly, folic acid can also reduce the risk of gene mutation in embryos. A study found that folic acid can help repair damage in DNA and reduce mutation. Gene mutation may lead to abnormal embryonic development and spontaneous abortion. Folic acid supplementation can reduce the risk of embryo gene mutation and reduce the possibility of abortion.
In addition, folic acid can also reduce the incidence of hypertension during pregnancy, which is also one of the common causes of IVF abortion. A study found that folic acid supplementation can reduce the risk of hypertension in pregnant women and further reduce the probability of miscarriage.
conclusion
In conclusion, folic acid plays an important role in the prevention of IVF abortion. Folic acid supplementation can improve the implantation ability of embryos, reduce the risk of gene mutation, and reduce the incidence of hypertensive disease during pregnancy. Therefore, it is very important for couples who plan to carry out IVF to start supplementation of folic acid in advance.
