Causes and Analysis of Low Success Rate of IVF
IVF technology is a kind of assisted reproductive technology, which realizes the dream of childbearing for many couples who cannot conceive naturally. However, with the growth of women's age, the success rate of IVF gradually decreases, especially for women over 42 years old, the chance of success is more limited. This article will explore the reasons for the low success rate of IVF from different aspects.
Decreased reproductive capacity
With the increase of age, the female reproductive ability begins to decline. This is due to the decrease in the number and quality of female eggs. After 42 years old, the number of female eggs has decreased to a very low level, and the quality is relatively poor. This means that it is more difficult to conceive and succeed in pregnancy, and it is difficult to achieve a higher success rate even through IVF technology.
In addition, women over 42 years old are often accompanied by other health problems, such as hypertension, diabetes and cardiovascular diseases, which may have adverse effects on pregnancy and embryonic development, further reducing the success rate of IVF.
Therefore, with the growth of age, the decline of female reproductive ability is one of the main reasons for the low success rate of IVF.
Egg quality decline
In addition to the decrease in the number, the egg quality of women over 42 years old also generally declined. The decrease of egg quality is mainly manifested in the increase of chromosomal abnormalities. The older you are, the higher the probability of chromosomal abnormalities, such as Down syndrome. Embryos with abnormal chromosomes are prone to spontaneous abortion or embryonic development disorders, so the success rate of IVF is significantly reduced.
In addition, the decline of egg quality will also lead to the reduction of sperm egg binding ability, reducing the chance of pregnancy. Therefore, the decline in egg quality is also an important factor in the low success rate of IVF.
Adverse uterine environment
The uterus environment of women over 42 years old may not be conducive to embryo implantation and development. The thickness of endometrium and blood supply decrease with age, which may affect the implantation of embryos on endometrium. In addition, uterine contraction function may also be affected with aging, which is not conducive to the fixation of embryos. These factors will reduce the success rate of IVF.
In addition, women over 42 years old are often accompanied by problems such as hysteromyoma and endometriosis, which also have a negative impact on the success rate of IVF. Therefore, the adverse uterine environment is also one of the reasons for the low success rate of IVF.
Sperm quality problems
In addition to female factors, male sperm quality may also affect the success rate of IVF. The quantity and quality of male sperm will change with age. The decrease of sperm quantity may reduce the chance of pregnancy, while the decrease of sperm quality may affect the development and health of embryos.
In men over 42 years old, there is often an increase in reproductive system diseases, such as abnormal sperm morphology and decreased sperm motility. These problems will have a negative impact on the success rate of IVF.
Summary:
To sum up, the main reasons for the low success rate of IVF include the decline of female reproductive ability, the decline of egg quality, the adverse uterine environment and the problem of male sperm quality. These factors are relatively more obvious in women over 42 years old. Therefore, for older couples, it is crucial to understand the impact of these factors, make full preparation and planning, and select appropriate hospitals and professional doctors for IVF.
