What is the impact of DHEA on the improvement of IVF results?
With the increase of infertility, IVF has become one of the common ways to solve the problem of infertility. As a hormone, DHEA (dehydroepiandrosterone) is believed to help improve the success rate of IVF. The impact of DHEA on IVF results will be described in detail from several aspects below.
Hormone regulation
DHEA is a precursor of adrenocortical hormone, which can be converted into male and female hormones and plays an important role in regulating female hormone levels. This hormonal regulation is critical to IVF outcomes. Studies have shown that the number and quality of follicles in women have improved after taking DHEA. The improvement of ovarian function helps to increase the production of normal logarithmic progesterone, improve the quality of fertilized eggs, and thus increase the success rate of IVF.
In addition, DHEA can also regulate the balance of female estrogen and androgen, and play an important role in the growth and preparation of endometrium. Healthy endometrium can provide a better implantation environment, thus increasing the pregnancy rate of IVF.
Ovarian reserve protection
The reduction of ovarian reserve is an important factor affecting female fertility. DHEA is believed to protect ovarian reserve through different mechanisms. First of all, DHEA has antioxidant and anti-inflammatory effects and plays a positive role in the protection of ovarian tissue. Secondly, DHEA can promote follicular development and increase the number and quality of eggs. Finally, DHEA can also prolong the time of ovarian aging and postpone the arrival of menopause.
A test tube baby study for DHEA treatment found that women taking DHEA had better response to ovarian stimulation, faster follicle growth, and increased ovarian reserve. These factors have had a positive impact on the results of IVF.
Improve egg quality
Egg quality is one of the key factors affecting the success rate of IVF. DHEA has the effect of improving the quality of eggs and plays a positive role in the maturation, fertilization and embryonic development of eggs.
One study observed the egg quality of women receiving DHEA treatment and women in the control group. The results showed that women receiving DHEA treatment had higher egg maturity, higher fertilization rate and higher embryo implantation rate. This shows that DHEA can help improve the egg quality and the success rate of IVF.
Use time and result improvement
As for the improvement of test tube infant results by the use time of DHEA, the current research results are inconsistent. Some studies believe that the longer DHEA is used, the greater the improvement of IVF results. For example, a study found that women who took DHEA for more than three months had a higher fertility success rate in IVF.
However, other studies have failed to observe a clear correlation between the duration of DHEA use and IVF outcomes. Therefore, further research is needed to verify the impact of DHEA use time on IVF results.
Summary
In conclusion, DHEA has a significant positive impact on the improvement of IVF results. Its role in regulating hormone balance, protecting ovarian reserve, improving egg quality and so on will help to improve the success rate of IVF. However, further research is needed to clarify the relationship between the use time of DHEA and the improvement of results. For couples who want to solve the problem of infertility through IVF, they can understand the use and effect of DHEA, select appropriate treatment methods and use them under the guidance of doctors.
