Effect of sperm quality on success rate of IVF
Test tube baby technology is an assisted reproductive technology, which has helped millions of couples successfully achieve their reproductive aspirations. Among them, the quality of sperm is one of the important factors affecting the success rate of IVF. This paper will elaborate on this impact from four aspects.
Survivability and athletic ability
The viability and motility of sperm are important indicators that affect the success rate of IVF. For sperm, whether it can survive in the female reproductive tract and successfully swim to the egg is crucial. Only the sperm with strong vitality can be successfully fertilized. Men with poor sperm quality may have low sperm viability, which will greatly reduce the possibility of fertilization. In addition, sperm with poor mobility will also lead to difficulties in the process of fertilization.
Doctors will evaluate sperm viability and motility through semen analysis. Common detection indicators include sperm density, sperm vitality, sperm morphology, etc. If the sperm quality is poor, the doctor may recommend the patient to take measures to improve the sperm quality, such as improving living habits and reducing stress.
DNA damage
Poor sperm quality may lead to DNA damage in sperm, which will also have a negative impact on the success rate of IVF. The damage of sperm DNA can be inherited or caused by acquired factors. If there is DNA damage, the sperm may not be able to activate the egg normally, leading to fertilization failure or difficulty in embryo implantation.
Some hospitals will test the sperm DNA damage of patients to assess the genetic quality of sperm. If DNA damage is found, doctors may suggest that patients take some auxiliary treatment measures, such as antioxidant treatment or sperm DNA damage repair technology, to improve sperm quality.
Chromosomal abnormality
Chromosome abnormality in sperm is also one of the important factors affecting the success rate of IVF. Chromosome abnormalities refer to the abnormal number or structure of chromosomes in sperm, such as polysomal syndrome and structural rearrangement. This abnormality may lead to the problem of embryo formation, making the embryo unable to develop normally.
In the chromosomal abnormality examination, the doctor will conduct karyotype analysis or FISH (fluorescence in situ hybridization) test on the patient's sperm to assess the risk of chromosomal abnormality. If chromosomal abnormalities are found, doctors may suggest that patients take some methods, such as sperm screening or dish preparation technology, to select sperm with normal chromosomes.
Influence the quality of embryos
Poor sperm quality may also affect the quality of embryos, which indirectly affects the success rate of IVF. Problems in sperm may lead to abnormalities in the process of fertilization, which may lead to the reduction of embryo quality. The embryos with poor quality are likely to fail to develop normally, or even to be implanted successfully after transplantation.
Doctors usually evaluate the quality of embryos during IVF to ensure that the most favorable embryos are selected for transplantation. If the evaluation result shows that the embryo quality is poor, the doctor will timely adjust the program, such as using embryo culture technology or chromosome detection, to improve the quality and success rate of the embryo.
summary
Sperm quality plays a key role in the success rate of IVF. The viability and motility, DNA damage, chromosome abnormalities and embryo quality are all affected by sperm quality. Therefore, if the male in the couple has poor sperm quality, it is recommended to consult a professional doctor as soon as possible and take appropriate treatment measures to improve the success rate of IVF.
