Effects of premature ovarian failure on IVF cycle and drug dosage
It is a common phenomenon that the ovarian function gradually declines with the growth of women's age. However, some women may face the problem of premature ovarian failure, that is, early ovarian failure. Premature ovarian failure will have a certain impact on IVF cycle and drug dosage.
1. Test tube baby cycle extension
Premature ovarian failure means that the quantity and quality of women's ovarian reserves will be reduced. This factor will lead to the prolongation of IVF cycle, because more attempts and longer time are needed to obtain enough eggs.
Normally, normal women only release one egg per month, while in IVF process, multiple eggs are needed to increase the possibility of pregnancy. For women with premature ovarian failure, the number of eggs is limited, so it may take many attempts to collect enough eggs.
In addition, women with premature ovarian failure may need to experience more cycles to achieve the goal of successful pregnancy. Because of the decline of ovarian function, the regulation of hormone levels and the quality of eggs may be affected, thus leading to the prolongation of IVF cycle.
2. Drug dose increase
The decline of ovarian function in patients with premature ovarian failure means that the regulation of hormone levels requires higher doses. In IVF, hormonal ovulation promoting drugs are usually used to stimulate the ovaries to produce more eggs. However, women with premature ovarian failure may need higher doses of drugs to achieve the same effect.
Increasing the dosage of drugs may increase some risks and side effects. Hormone ovulation promoting drugs may cause ovarian hyperstimulation syndrome (OHSS), which is a rare but serious complication. Therefore, when giving drugs to women with premature ovarian failure, doctors will be more careful and closely monitor the dosage and effect of drugs.
3. Decreased pregnancy success rate
Premature ovarian failure will have a negative impact on the success rate of IVF. Due to the decline of ovarian function, the quality and quantity of eggs will be reduced, which means that the chance of pregnancy is less.
According to research, women with premature ovarian failure have a lower fertility success rate and need to go through more cycles to achieve pregnancy. This may increase the psychological and economic burden of patients, because the IVF process usually requires a long time and financial support.
4. Increased psychological pressure
Premature ovarian failure is a huge psychological pressure for women who want to have children. The problem itself brings anxiety, disappointment and despair. At the same time, the IVF process is also a difficult journey for patients, who need to experience many attempts and disappointments.
Women with premature ovarian failure may need psychological counseling and support to help them cope with these psychological pressures. This includes emotional management, psychotherapy and family support, which are designed to help patients cope with challenges and maintain a positive attitude.
summary
Premature ovarian failure has a significant impact on IVF cycle and drug dosage. The decline of ovarian function will lead to the prolongation of IVF cycle, and the drug dose needs to be increased. The success rate of pregnancy will also decrease, increasing the psychological pressure of patients. Therefore, for women with premature ovarian failure, early diagnosis and active treatment are essential, while strengthening psychological support is also essential.
