What is premature ovarian failure
Premature ovarian failure, also known as ovarian insufficiency, refers to the deterioration of ovarian function when women are young, leading to irregular menstruation, early menopause and infertility. The main causes of premature ovarian failure include chromosome abnormalities, genetic factors, autoimmune diseases and environmental factors.
The patients with premature ovarian failure have a low probability of natural pregnancy due to their low ovarian function, so the IVF technology has become the preferred method to solve the problem of infertility in patients with premature ovarian failure.
Principles of IVF technology
In vitro fertilization embryo transfer technology. First, fertilize a female egg with a male sperm in the laboratory to form a fertilized egg; Then, the fertilized eggs are cultured to the appropriate embryonic development stage; Finally, the qualified embryos will be transferred to the female uterus, so that they can continue to develop and eventually become pregnant.
Test tube baby technology is carried out in patients with premature ovarian failure, mainly through ovulation promoting drugs to stimulate ovarian development, so that the ovary can produce enough eggs. Then, eggs are collected for in vitro fertilization, and appropriate embryos are selected and transferred to the uterus to increase the success rate of pregnancy.
Advantages of IVF technology for patients with premature ovarian failure
First, IVF technology can overcome the problem of poor ovarian function in patients with premature ovarian failure and improve the chance of pregnancy. Stimulating ovarian development by using ovulation promoting drugs can increase the number of eggs and improve the success rate of fertilization and embryo transfer.
Secondly, IVF technology can select suitable embryos for transplantation. In the process of embryo culture, healthy embryos can be selected through embryo quality assessment for transplantation, which improves the probability of successful pregnancy.
In addition, IVF technology can bring more safety to patients with premature ovarian failure. In the process of IVF technology, doctors will strictly monitor the ovarian response of patients, reducing the risk of treatment.
Success rate of IVF in patients with premature ovarian failure
IVF technology has a relatively high success rate in patients with premature ovarian failure. According to the statistics of some well-known hospitals in China, in the normal age range (less than 40 years old), women with premature ovarian failure have a test tube baby, and the probability of successful pregnancy is about 30%~60%.
For example, according to the data from the Department of Obstetrics and Gynecology of Peking Union Medical College Hospital, about 40% of patients with premature ovarian failure who received IVF treatment successfully became pregnant. Similarly, Xinhua Hospital affiliated to Shanghai Jiaotong University School of Medicine reported a similar success rate.
However, the success rate of IVF technology is affected by many factors, such as female age, ovarian function, accompanying diseases, etc. Therefore, the specific success rate needs to be evaluated according to individual conditions.
Summary
Patients with premature ovarian failure can overcome the problem of poor ovarian function and improve the chance of pregnancy through IVF technology. The principle of technology makes it easier to combine eggs and sperm, and the selection and cultivation of suitable embryos can improve the probability of successful pregnancy. Although the success rate is related to individual conditions, according to existing data, IVF technology has a high success rate in patients with premature ovarian failure.
