What disease genetic problems can PGD IVF solve?
In recent years, with the continuous progress of science and technology, the application of PGD (Preimplantation Genetic Diagnosis) test tube baby technology is more and more extensive. PGD test tube baby technology selects embryos carrying specific genetic diseases through genetic testing of embryos, and only healthy embryos are implanted into the mother, thus solving a series of problems of genetic diseases. The following is a detailed description of the genetic diseases that PGD IVF can solve from four aspects.
1. Single gene genetic disease
Many genetic diseases are caused by mutations in a single gene. The incidence of these diseases is high, which has a serious impact on patients. PGD test tube baby technology can avoid implanting embryos with genetic mutations into the mother through genetic screening. For example, PGD test before blastocyst transplantation can detect common monogenic genetic diseases such as thalassemia and cystic fibrosis, and help families avoid disease risks.
In addition, through PGD test tube baby technology, embryos carrying genetic mutations can be screened out, while only normal embryos can be implanted into the mother, thus improving the success rate and reducing the risk of adverse pregnancy.
2. Chromosome abnormalities
Chromosome abnormality is one of the common causes of abnormal embryonic development and abortion. PGD test tube baby technology can detect the chromosomes of blastocysts and select embryos with normal chromosomes for implantation, so as to improve the success rate of pregnancy and reduce the risk of embryo malformation and abortion.
For example, PGD technology can detect embryos with abnormal chromosome numbers such as Down's syndrome and Edwards syndrome, and exclude these embryos, and only select embryos with normal chromosomes for implantation. In this way, the risk of chromosomal abnormalities in children born to patients can be reduced.
3. Hereditary tumor
Many tumors are caused by genetic mutations. If there is gene mutation of hereditary tumor disease in the patient's family, PGD technology can be used to screen out the embryos carrying this mutation and avoid implanting them into the mother. In this way, the inheritance risk of hereditary tumor disease will be greatly reduced.
For example, in the PGD technology implemented by a hospital, BRCA1 and BRCA2 genes can be screened. These two gene mutations are closely related to hereditary tumors such as breast cancer and ovarian cancer. With the help of PGD technology, it can reduce the chance of embryos carrying these gene mutations being implanted into the mother, and reduce the risk of hereditary tumors in families.
4. Rare genetic diseases
In addition to common single gene hereditary diseases, chromosome abnormalities and hereditary tumors, PGD test tube baby technology can also solve some rare hereditary diseases. For these rare genetic diseases, doctors can use specific genetic testing methods to select suitable embryos for implantation. This provides a safe and feasible choice for families with rare genetic diseases.
In a word, PGD test tube baby technology has solved a series of hereditary diseases such as single gene hereditary diseases, chromosome abnormalities, hereditary tumors and rare hereditary diseases through genetic testing of embryos. The popularization and application of this technology has brought new hopes and choices to many families.
