1、 Influencing factors of male female ratio in test tube infants
IVF refers to the process of culturing fertilized eggs in vitro through assisted reproduction technology and selecting the best embryo to implant into the mother. In real life, people generally pay attention to the male female ratio of IVF. What is the difference between the male female ratio of IVF and IVF? First of all, the male female ratio of IVF is not completely controlled manually, but affected by many factors.

First, the male female ratio of IVF is affected by the genetic factors of parents. If there are genetic diseases with chromosome abnormalities in male relatives, such as chromosome aneuploidy, sex chromosome abnormalities, etc., the probability of giving birth to a boy will increase. At the same time, maternal genetic factors may also affect the sex differentiation of embryos. For example, maternal chromosome aneuploidy or genetic diseases may also lead to gender bias in infants.
Secondly, the male female ratio of IVF is also affected by technical factors in the process of IVF. In the process of IVF, the skill level and temperature of doctors during egg retrieval and sperm injection may affect the sex of fertilized eggs. These technical factors may cause the number of embryos of one sex to be more than that of the other, thus affecting the ratio of male to female IVF babies.
In addition, the male female ratio of IVF may also be subject to the legal constraints of the legality of IVF's sex selection. In some countries and regions, sex selective IVF may be restricted by law, and can only choose gender equal implantation. In some countries, the technology of screening the sex of embryos is allowed, which may lead to a large difference in the proportion of men and women in IVF.
2、 Status quo of male female ratio of test tube babies
There are some differences in the proportion of men and women in IVF in the world. For example, according to the data of the National Assisted Reproductive Technology Monitoring System established by the United States, between 1995 and 2014, the proportion of men and women in IVF showed a slight bias towards men, about 51.5%. In a study in Nepal, the ratio of male to female test tube babies was 50.7%. In some areas of China, due to the family's pursuit of male inheritance and other factors, the male to female ratio of IVF is more obvious.
The male female ratio of IVF has a certain trend of change. With the continuous progress and standardization of assisted reproductive technology, the relevant gender selection technology has also been improved. It is generally believed that the success rate of gender screening will become higher over time, which is expected to change the ratio of men and women in IVF to some extent.
3、 Influence mechanism of male female ratio in test tube infants
The imbalance of the ratio of men and women in IVF may be related to the interaction of multiple factors. First, the factors of artificial selection may affect the sex differentiation of embryos to some extent. For example, in the process of in vitro culture, embryos of a certain sex may be more likely to develop and mature, and thus be subject to more choices for further development.
Secondly, the male female ratio of IVF may also be affected by women's internal environment. Research shows that maternal hormone levels, endometrial thickness and other factors are related to the sex of IVF. For example, high estrogen levels may increase the chances of having a boy, while high progesterone levels may increase the chances of having a girl.
Finally, the male female ratio of IVF is also affected by the genetic factors of embryos. The sex chromosome structure and related genes encoded by chromosomes carried by embryos may also play a role in the process of embryo sex differentiation.
4、 Summary
To sum up, the difference between the male and female ratio of IVF and IVF is mainly reflected in the following aspects. First, the male female ratio of IVF is affected by many factors, including genetic factors, technical factors and legal factors. Secondly, there are some differences in the proportion of male and female test tube babies worldwide, but the overall trend is gender balance. Thirdly, the imbalance of the male female ratio of IVF may be related to the factors of artificial selection, female internal environment and genetic factors of embryos. Finally, with the progress and standardization of assisted reproductive technology, the male female ratio of IVF is expected to be improved and adjusted.