How many attempts does a single sperm test tube baby need?
Single sperm test tube baby is a kind of assisted reproductive technology, which is suitable for the condition of low quantity or quality of male sperm. Before the single sperm test tube baby, it usually needs a series of attempts to increase the chance of success. However, the number of attempts required will vary depending on the situation of each individual. The following will elaborate on sperm supply, operation technology, selection of in vitro fertilization and hospital implementation.
Number of sperm supply
Sperm donation refers to the semen samples provided by male patients as the source of single sperm test tube babies. The quality and quantity of semen supply have an important impact on the success rate. Generally, doctors will require male patients to provide semen samples after a certain abstinence period to ensure the quality of sperm. If the sample of semen supplied at one time is insufficient or of poor quality, the doctor may suggest another attempt. This means that the number of times of sperm donation may need to be repeated to obtain high-quality sperm samples.
In addition, some male patients may have the need for assisted technologies such as intratesticular sperm extraction (TESA) or testicular biopsy (TESE). These technologies can extract single sperm from testis through surgery, and can obtain better quality sperm for IVF process. However, due to the large individual differences in these techniques, it may take several attempts to successfully extract a single high-quality sperm.
Operation technology
Operation technology refers to the technology and method used by doctors in the process of in vitro fertilization. In vitro fertilization can be divided into two modes: conventional in vitro fertilization (IVF) and intracellular sperm injection (ICSI). In conventional IVF, eggs and sperm are naturally combined in a culture dish; In ICSI, a sperm is injected directly into the egg. Select which technique to use according to specific cases and doctor's recommendations.
In conventional IVF, the probability of success is relatively low due to the free combination of sperm and egg. Therefore, conventional IVF usually requires multiple attempts to succeed. In ICSI, each egg can be injected with a sperm, which increases the chance of success. Therefore, ICSI requires relatively few attempts for IVF with single sperm.
Selection of in vitro fertilization
In vitro fertilization of single sperm test tube infants, fresh sperm or frozen sperm can be used. Fresh sperm refers to the sperm samples provided by patients within a specific time, and frozen sperm refers to the sperm samples stored in advance.
The advantage of using fresh sperm for IVF is that the quality of sperm is relatively higher. However, the acquisition of fresh sperm may require several attempts, because the sperm production of male patients is limited. On the other hand, the use of frozen sperm for IVF can reduce the limit of sperm supply, but the quality of sperm may be affected by the freezing and thawing process. Therefore, whether to use fresh sperm or frozen sperm according to the specific situation needs to be determined based on the actual situation of the patient.
Hospital implementation
Single sperm test tube baby is a highly professional technology, which needs to be operated in regular hospitals or reproductive centers. There will be differences in the implementation standards, operation levels and equipment conditions between different hospitals. Therefore, it is also very important to choose a suitable hospital before conducting IVF with single sperm.
Some well-known reproductive centers, such as Peking Union Medical College Hospital and Ruijin Hospital affiliated to Shanghai Jiaotong University School of Medicine, have high technical level and rich experience. In these hospitals, single sperm IVF can usually achieve better success rate and effect. Therefore, selecting a suitable hospital can also reduce the number of attempts to a certain extent.
Summary
The number of attempts needed by test tube monosperm infants varies from individual to individual. The key factors affecting the number of attempts are the number of sperm donation, operation technology, selection of in vitro fertilization and hospital implementation. The times of sperm donation may need to be repeated to obtain high-quality sperm samples; In operation technology, ICSI can reduce the number of attempts compared with conventional IVF; The selection of IVF needs to consider the advantages and limitations of fresh sperm and frozen sperm; When selecting hospitals, the professional level and experience of well-known hospitals can improve the success rate. To sum up, the number of attempts depends on individual conditions and the comprehensive impact of the above factors.
