Effect of polycystic ovary on the success rate of test tube infants
Polycystic ovary syndrome (PCOS) is a common reproductive system disease, which may affect the success rate of IVF. In vitro fertilization (IVF) is a common method of assisted reproductive technology (ART). The purpose of pregnancy is achieved by implanting eggs and sperm into the mother body after IVF. Patients with polycystic ovary syndrome will face a series of challenges in the process of IVF. Here we will discuss how polycystic ovary affects the success rate of IVF from several aspects.
Hormonal regulation
Polycystic ovary syndrome patients usually have the characteristics of hormone imbalance, such as the increase of androgen and the relative deficiency of estrogen. This hormone imbalance will affect the function of the ovary, leading to follicular dysplasia and ovulation disorders. In the process of IVF, the development of follicles and the normal ovulation are very critical. Therefore, polycystic ovary patients need drugs to regulate hormone levels and promote follicular growth and ovulation. However, inappropriate hormone regulation may lead to ovarian over response or delayed response, which has a negative impact on the success rate of IVF.
In order to reduce this impact, doctors will develop personalized treatment plans according to the specific conditions of patients, and adjust the dosage and use time of drugs by monitoring the follicle size and hormone level. Reasonable hormone regulation is critical to improve the success rate of IVF.
Egg mass
The quality of eggs in patients with polycystic ovary syndrome (PCOS) is generally poor, which is mainly manifested by the increase in the number of immature eggs. After in vitro fertilization, immature eggs often fail to develop into embryos or embryos develop slowly, leading to transplant failure or implantation failure. In addition, polycystic ovary syndrome patients may have genetic problems with egg quality, which will also affect the success rate of IVF.
In order to deal with this problem, doctors often take high-intensity assisted reproductive treatment methods, such as the use of ultra-high ovulation catheters and timely follicular extraction, to obtain more mature eggs. When selecting eggs, doctors will also screen them according to their quality and shape, and select the eggs most likely to develop into embryos for in vitro fertilization. These measures can improve the success rate of IVF in patients with polycystic ovary.
Uterine environment
Patients with polycystic ovary syndrome may have problems such as endometriosis and uterine cavity malformation, which will affect the uterine environment and reduce the implantation rate of embryos. An important factor in the success rate of IVF is the implantation of embryos in the uterus. If the uterine environment is poor, it is difficult for the embryo to successfully implant and develop into pregnancy.
Patients with polycystic ovary usually receive hysteroscopy before IVF to assess the health of endometrium and find and correct possible problems. If endometrial hyperplasia is found, doctors will treat it through surgery to create a good uterine environment and improve the success rate of IVF.
psychological support
Patients with polycystic ovary syndrome are often accompanied by stress and anxiety during IVF. Periodic failure and futile efforts may lead to depression of patients, further affecting the success rate of IVF. Psychological support is very important in IVF.
In real hospitals, professional psychological consultants or psychologists will be provided to provide psychological guidance and support for patients with polycystic ovary syndrome. They will help patients relieve pressure, adjust their mentality and enhance their confidence. Research shows that good psychological status can improve the physiological status of patients and improve the success rate of IVF.
summary
Polycystic ovary syndrome has a greater impact on the success rate of IVF. Hormone regulation, egg quality, uterine environment and psychological support are the key factors to solve the success rate of IVF in patients with polycystic ovary syndrome. The success rate of IVF in patients with polycystic ovary syndrome can be improved to a certain extent by personalized treatment, improving egg quality, improving uterine environment and psychological support.
