The best scheme of IVF treatment for patients with polycystic ovary syndrome
Polycystic ovary syndrome (PCOS) is a common disease of female reproductive system, and patients often have ovulation disorders and abnormal androgen levels. For patients with PCOS, IVF treatment is an effective assisted reproductive technology. For the special needs of PCOS patients, the following is a good plan, including diagnosis and evaluation, adjuvant drug therapy, hormone regulation and personalized auxiliary technology. Through the comprehensive application of these aspects, the success rate of IVF treatment can be improved.
1. Diagnosis and evaluation
For patients with PCOS, a comprehensive diagnosis and evaluation is needed first to determine whether it is suitable for IVF treatment. Gynecologists in the hospital can make a diagnosis through detailed medical history inquiry, physical examination and relevant examination items. Common assessment items include blood hormone level detection, ultrasonic examination and exclusion of other potential causes. The purpose of the evaluation is to determine the patients' basic ovarian reserve and endometrial status, and provide guidance for the selection of follow-up treatment plans.
In the evaluation, doctors will develop personalized treatment plans according to the specific conditions of patients. Drug assisted therapy is a common choice, which can help patients improve ovulation function, adjust androgen level, and improve the success rate of treatment.
2. Drug assisted treatment
Drug assisted therapy is an important part of IVF treatment for patients with polycystic ovary syndrome. Common drugs include insulin sensitizers and antiandrogens.
Insulin sensitizers, such as metformin, can improve insulin sensitivity and ovulation function. It can also reduce androgen synthesis and alleviate the symptoms of metabolic disorders, and help control PCOS related metabolic diseases, such as obesity and diabetes.
Anti androgen drugs, such as estrogen receptor antagonists, can inhibit the effect of androgen and reduce the androgen produced by the ovary. These drugs can improve ovulation by reducing progesterone production and inhibiting prolactin secretion.
Drug assisted treatment is usually carried out under the control of cycle, and doctors will make drug selection and dosage adjustment according to the specific conditions of patients to improve the ovulation rate and pregnancy rate of patients.
3. Hormone regulation
PCOS patients are often accompanied by abnormal hormone levels, especially high androgen levels and low progesterone levels. Hormone regulation is an essential step in IVF treatment.
Common hormone regulation schemes include artificial cycle guidance and luteal support after embryo transfer. Artificial cycle guidance is to guide follicular development and ovulation by giving exogenous hormones, such as ovulation promoting drugs. Luteal support is to give progesterone and other luteal support drugs after embryo transfer to maintain the stability of endometrium and promote fetal implantation.
Hormone regulation needs to be combined with patients' ovarian reserve and embryo quality to determine specific programs to improve the success rate of embryo transfer.
4. Personalized auxiliary technology
For patients with PCOS, personalized assistance technology can further improve the success rate of IVF treatment. Common personalized assistant technologies include embryo chromosome screening, thin layer endometrial transplantation and embryo blastocyst transfer.
Embryonic chromosome screening can help screen out embryos with abnormal chromosomes, so as to select better quality embryos for transplantation, improve the pregnancy rate and reduce the risk of abortion.
Thin layer endometrial transplantation is a special technique for PCOS patients, which can improve the problem of insufficient endometrial thickness. This technique can improve the success rate of embryo implantation and pregnancy rate.
Embryo blastocyst transfer is a more advanced method of transfer. Embryos are cultured to a higher development stage before transfer. This technique can improve the implantation rate and pregnancy rate of embryos.
Summary
The best treatment options for IVF in patients with polycystic ovary syndrome include diagnosis and evaluation, adjuvant drug therapy, hormone regulation and personalized adjuvant technology. Diagnosis and evaluation can help doctors understand patients' conditions and develop personalized treatment plans. Adjuvant medication can improve ovarian function and adjust hormone levels. Hormone regulation is an important link to ensure the success of embryo transfer. Personalized assisted technology can further improve the success rate of IVF treatment. Through the comprehensive application of these methods, we can provide the most suitable treatment scheme for patients with polycystic ovary syndrome and improve the success rate of fertility.
