introduction
As an important part of assisted reproductive technology, IVF technology has made remarkable achievements in solving the problem of infertility. With the progress of science and technology, the third generation of IVF technology came into being. This article will discuss the differences between the third generation IVF and traditional IVF in four aspects. First aspect: embryo screening
In traditional IVF technology, the choice of which embryo to implant into the mother mainly depends on the appearance of the embryo, that is, the shape and structure. This kind of judgment accuracy is relatively low. The third generation IVF technology uses PGS (embryo chromosome screening) and PGD (single gene disease prediction) technologies, which can more accurately assess the genetic health of embryos and avoid the implantation of embryos with genetic diseases. In addition, the third generation IVF technology can also screen better embryos and improve the success rate by detecting factors such as micro defects, chromosome structure abnormalities and gene mutations. In traditional IVF technology, multiple embryos will be implanted into the uterine cavity at one time. The third generation of IVF technology introduces the strategy of single embryo transfer. This means that only the healthiest embryo will be implanted under certain conditions, reducing the risk of multiple pregnancy. This can not only reduce the risk of complications for both mothers and infants, but also improve the success rate of pregnancy.
In addition, the third generation IVF technology also selects embryos with higher embryonic development potential for implantation by extending the embryonic development time. This can further improve the success rate of IVF.
The second aspect: intima preparation
In traditional IVF technology, endometrial preparation mainly depends on the use of exogenous hormone drugs. This method often takes a long time, which is easy to cause physical and psychological pressure of patients. The third generation of IVF technology uses natural cycle intima preparation, that is, using women's own natural cycle, without the use of exogenous hormone drugs to intervene, which reduces the physical burden and discomfort of patients. In the third generation IVF technology, in order to improve the success rate of implantation, intimal ischemia reperfusion technology is sometimes used. By injecting specific fluid into the uterine cavity, it can promote the increase of endometrial blood flow and improve the success rate of embryo implantation.
Third aspect: cell culture
In traditional IVF technology, embryo culture is generally conducted in an in vitro incubator, which does not provide personalized environment and nutritional requirements. The third generation of IVF technology has introduced a dynamic nest culture system (transparent intrauterine culture, time lap technology), which can monitor the development of embryos in real time and provide a culture environment closer to the natural environment. This individualized and real-time monitoring culture mode is helpful to identify the developmental potential of embryos and select the best time for implantation. Fourth aspect: frozen embryo reproduction
In traditional IVF technology, people often use fresh embryo transfer. However, fresh embryo transfer needs to accurately grasp the ovulation period of women, which puts forward higher requirements for doctors and patients. In the third generation of IVF technology, frozen embryo transfer is used to freeze the embryos, and the implantation time is selected according to the patient's physiological conditions and endometrial status, which improves the success rate of implantation and embryo implantation rate. At the same time, the use of frozen embryos can also avoid the limitation of ovulation cycle, providing greater flexibility. summary
Compared with traditional IVF technology, the third generation IVF technology has significant differences in embryo screening, intima preparation, cell culture and frozen embryo reproduction. With the help of advanced technology, the third generation IVF technology has improved the success rate of IVF and the safety of patients, and also made infertile couples more hopeful to realize their reproductive dreams.
