Older IVF babies - how to improve the success rate?
IVF technology has become the last lifeline for many infertile couples to realize their dreams. However, for older women, the success rate is relatively low. Therefore, there are some key measures to help improve the success rate for older IVF infants.
Selection of high-quality embryos
In the process of IVF, it is crucial to select high-quality embryos. In order to improve the success rate, women need to take eggs many times. The doctor will evaluate the ovarian response and provide the best ovulation promotion scheme. In the process of fertilization, appropriate culture conditions and detection techniques can ensure the quality of embryos. Some hospitals, such as Peking Union Medical College Hospital and Ruijin Hospital affiliated to Shanghai Jiaotong University School of Medicine, have made good technological breakthroughs in this regard.
In addition, single nucleotide polymorphism paternity testing (DNA paternity testing) can help improve the selection of embryo quality. This technology reduces the chance of embryo development failure caused by chromosome abnormalities or gene defects by detecting the chromosome composition and gene mutation of the embryo. For example, the Obstetrics and Gynecology Hospital affiliated to the Medical College of Zhejiang University has introduced DNA paternity testing technology, which has greatly improved the success rate of older test tube babies.
In addition, more and more hospitals are trying to use artificial intelligence technology to assist embryo selection. Through image recognition and data analysis of a large number of embryos, we can more accurately assess their development potential and health status. The artificial intelligence assisted embryo screening technology of Peking Union Medical College Hospital has achieved good results in practice.
Careful care and accurate operation
Careful nursing and accurate operation are the basis for the success of the elderly IVF. The doctor needs to pay attention to the patient's physical condition and reaction in the whole process, and adjust the treatment plan in time. At the same time, medical personnel need to do a good job of intraoperative operations to ensure the accuracy of each step.
Some doctors will also develop personalized treatment plans according to the specific conditions of patients. For example, Beijing Chaoyang Hospital affiliated to Capital Medical University has implemented a set of advanced IVF programs called "Top". The program improves the success rate of elderly IVF infants by taking precise measures such as ovarian suppression, transplantation cycle control, and prevention and treatment of fetal arrest.
Application of auxiliary technology
Assisted technology is one of the important means to improve the success rate of older IVF infants. A commonly used auxiliary technology is Preimplantation Genetic Diagnosis (PGD). PGD can screen chromosome abnormalities of embryos, provide choices for healthy embryos, reduce the risk of abortion, and reduce the incidence of congenital diseases caused by chromosome abnormalities.
In addition, the assisted accumulation technology can be used to improve the uterine environment and increase the embryo implantation rate. These techniques include endometrial cuticle relaxants, and bed rest after whitening control surgery. For example, Ruijin Hospital affiliated to Shanghai Jiaotong University School of Medicine carried out a study that combined assisted accumulation technology and PGD to provide better therapeutic effects for older IVF infants.
Healthy lifestyle and psychological support
Healthy lifestyle also plays a positive role in improving the success rate of older IVF infants. Women need to maintain proper exercise and a balanced diet to maintain health and endocrine balance. In addition, smoking, excessive drinking and long-term exposure to environmental pollutants should be avoided.
In the process of IVF, emotion and psychological state have certain influence on the success rate. Therefore, it is very important to provide psychological support and guidance. Some hospitals have psychological consultants to help patients adjust their emotions, relieve stress, and enhance confidence and determination. The psychological counseling center of Peking Union Medical College Hospital provides professional psychological support for the elderly IVF patients.
Summary
For the elderly test tube infants, improving the success rate mainly includes the selection of high-quality embryos, careful care and accurate operation, the application of auxiliary technology, healthy lifestyle and psychological support. Through the technical breakthrough of the hospital and the formulation of comprehensive treatment plan, the success rate of elderly IVF babies has been continuously improved, bringing more hope for infertile couples to realize their reproductive dreams.
