How to evaluate the feasibility of IVF technology for big three positive patients?
Test tube baby technology has become an effective means to solve some infertility problems. However, for the big three positive patients, because they are infected with HIV, hepatitis B virus and syphilis, whether they can successfully conceive through test tube baby technology needs to be evaluated in detail. The feasibility of IVF technology for big three positive patients is described in the following four aspects.

1. Impact of virus infection on IVF
First of all, the virus infection status of patients with Big Three Positive has a direct impact on the success rate of IVF. HIV, HBV and syphilis can be transmitted to embryos through genital secretions, affecting their implantation and development. Therefore, before IVF, it is necessary to assess the degree of infection and select appropriate treatment measures, such as antiviral treatment, to reduce the risk of virus transmission.
Secondly, the virus infection of big three positive patients will also have a certain impact on the operation of IVF technology. HIV and hepatitis B virus can be transmitted through blood and body fluids, while IVF technology requires operations such as egg retrieval and embryo transfer, which requires strengthening protective measures during the operation to avoid infection risks of medical staff and ensure the safety of the operation.
Finally, HIV and hepatitis B virus will also have an impact on the health of newborns. Viral infection will increase the risk of embryo infection in utero, leading to an increased likelihood of birth defects and infant infection. Therefore, before IVF, it is necessary to evaluate the viral infection status of patients, and closely monitor and treat with antiviral therapy during pregnancy to reduce the risk of neonatal infection.
2. Selection and application of assisted reproductive technology
The IVF technology for patients with Big Three Positive should be customized and applied according to their viral infection. For patients with high viral load, PGD/PGS technology, a preimplantation genetic diagnosis method in assisted reproductive technology, can be considered to screen healthy embryos for transplantation and reduce the risk of infant infection.
In addition, for patients with mild virus infection or who have received antiviral treatment, in vitro fertilization embryo transfer (IVF-ET) technology in assisted reproductive technology can be considered to reduce the risk of virus transmission. Before transplantation, embryos should be fully cultured and screened, and healthy embryos should be selected for transplantation to improve the success rate of pregnancy.
At the same time, for those infected with hepatitis B, we can also consider the use of test tube baby technology with artificial cycle regulation, and choose an appropriate time for embryo transfer. This method improves embryo implantation and pregnancy rate through antiviral treatment and hormone regulation.
3. Pregnancy management and risk control
After successful pregnancy, the management and risk control during pregnancy are very important. First, antiviral treatment for pregnant women needs to be strengthened to control the risk of virus replication and infection. At the same time, prenatal examination should be carried out regularly to monitor the development and virus infection of the fetus, and timely measures should be taken to protect the health of the fetus.
In addition, it is also necessary to consider choosing an appropriate mode of delivery. Since patients with Big Three Positive are infected with hepatitis B virus, there is a risk of vertical transmission. Therefore, cesarean section can be considered to reduce the possibility of fetal infection.
4. Psychological support and welfare security
Successful pregnancy is a major psychological and physical challenge for patients with big three yang. Therefore, it is necessary to provide good psychological support. The hospital can set up collective rehabilitation courses, organize psychological counseling, communication and mutual assistance for patients with big three yang, and help them through the difficult process of seeking children.
At the same time, it is also very important to protect the welfare rights of patients with big three positive in the process of IVF. The hospital should strengthen the protection of the privacy of patients with Big Three Yang to ensure that information is not leaked. In addition, the hospital can also establish a special case assistance fund to provide financial support for patients with severe financial difficulties.
Summary
To sum up, for patients with big three positive, the feasibility of IVF technology needs to be comprehensively evaluated from the impact of virus infection on IVF, the selection and application of assisted reproductive technology, pregnancy management and risk control, as well as psychological support and welfare security. These assessments can help doctors and patients work together to develop reasonable plans and treatment plans, improve the success rate of IVF, and ensure the health and well-being of mothers and infants.