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IVF antagonist protocol What methods are used in IVF antagonist protocol?

IVF antagonist protocol What methods are used in IVF antagonist protocol?



IVF antagonist protocol

The IVF antagonist program is a commonly used method in assisted reproductive technology, which aims to regulate female ovarian function, promote follicular growth and ovulation, and increase the chance of IVF pregnancy. The application of IVF antagonist scheme will be described in detail in the following four aspects: drug selection, dosage regulation, monitoring means and indications.

Drug selection

The commonly used drugs in the IVF antagonist scheme are gonadotropin releasing hormone antagonists (GnRH antagonists), such as cetorelix and ganirelix. These drugs can inhibit ovulation and regulate follicular development by inhibiting the secretion of gonadotropin and preventing the formation of corpus luteum. In the conventional protocol, GnRH antagonists are used before the initial ovulation, generally starting from the 5th to 7th day of ovarian stimulation. The selection and dosage of drugs should be adjusted according to individual conditions and doctor's recommendations.

Dose control

In the IVF antagonist regimen, dosage regulation is crucial. The appropriate dose is generally determined according to the age of women, ovarian reserve and ovulation process. Low dose may lead to inadequate follicular development, while high dose may lead to more than three follicles mature, increasing the risk of multiple births. When using GnRH antagonists, it is also necessary to determine the dosage of hormone according to the basic follicle count and weight of women. By monitoring the development of follicles and changes in blood hormone levels, doctors can adjust the dosage of drugs in time in order to obtain good therapeutic effects.

Monitoring means

The IVF antagonist protocol needs to closely monitor the changes of ovarian function and the growth of follicles in order to adjust the drug dose and treatment program in time. Common monitoring methods include ultrasonic monitoring and blood hormone detection. Ultrasound monitoring through regular vaginal ultrasound examination, observe the number and size of follicles changes, judge the maturity of eggs. At the same time, it can also assess the thickness and blood flow of the endometrium, creating a good environment for embryo implantation. Blood hormone detection mainly monitors the changes of follicle stimulating hormone (FSH), luteinizing hormone (LH) and estrogen levels to judge the development of follicles and control the effect of ovarian stimulation.

indication

The IVF antagonist scheme is applicable to women with many difficulties in pregnancy, such as polycystic ovary syndrome, premature ovarian failure, fallopian tube obstruction, etc. At the same time, the scheme can also be used to select patients who donate eggs and embryos to improve the success rate of transplantation and pregnancy. In addition, in assisted reproductive technology, IVF antagonist program can also be combined with other adjuvant treatment methods to further improve the success rate of IVF. In conclusion, IVF antagonist programs are widely used in assisted reproductive technology. Through reasonable selection of drugs, accurate control of dosage, effective monitoring of ovarian function and follicle growth, and clear indications, the chance of IVF pregnancy can be increased, bringing good news to infertile patients.
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