Test tube baby test item type
Test tube baby inspection items refer to a series of inspection items for test tube baby embryos or patients through medical technology. The examination of IVF embryos mainly includes embryo gene detection, chromosome structure analysis and preimplantation genetic diagnosis; The examinations for patients mainly include genetic disease screening, hormone testing and endometrial testing.
Test tube baby examination items are mainly divided into the following categories:
1. Embryo gene detection
Embryo gene testing is the genetic testing of genetic diseases on IVF embryos to screen or exclude patients with embryonic genetic diseases. Such inspection items include single gene disease detection, polygenic disease detection and chromosome structure detection. Single gene disease detection is mainly aimed at common genetic diseases such as thalassemia, cystic fibrosis, etc. Through the detection of embryonic genes, embryos without disease genes are screened for transplantation. Multigene disease detection involves detection of multiple genes, such as Down syndrome and congenital heart disease. Chromosome structure detection is mainly to detect whether there are structural abnormalities in embryonic chromosomes, such as chromosome deletion, translocation, duplication, etc.
2. Preimplantation genetic diagnosis
Preimplantation genetic diagnosis is to assess the health status of embryo development and potential genetic risks through the detection of IVF embryos. Such inspection items mainly include embryo quality assessment and preimplantation genetic diagnosis. Embryo quality assessment assesses embryo quality by observing embryo development, cell number, embryo morphology and other indicators, so as to select the most suitable embryo for transfer. Preimplantation genetic diagnosis is to determine whether there are genetic diseases or chromosomal abnormalities in the embryo by detecting the genetic material of the embryo, such as embryo nucleus, cytoplasm and embryo culture medium.
3. Genetic disease screening
Genetic disease screening refers to screening test tube baby patients for genetic diseases to assess whether there is a risk of genetic diseases. Such inspection items mainly include common genetic disease screening, neonatal genetic disease screening and genetic sequencing. Common genetic disease screening is mainly to screen common genetic diseases, such as phenylketonuria, congenital hypothyroidism, etc. Neonatal genetic disease screening is mainly conducted after the birth of a baby to detect whether the baby has congenital metabolic defects. Genetic sequencing is to screen relevant genetic variations and assess the genetic risk of patients by sequencing and analyzing the genome DNA of patients.
4. Hormone detection and endometrial detection
Hormone testing and endometrial testing are mainly for IVF patients. Hormone testing is mainly to evaluate the endocrine status of patients, including the detection of follicle stimulating hormone, estrogen and luteinizing hormone, to determine the best pregnancy cycle and treatment plan. Endometrial detection is to evaluate the endometrial status and implantation adaptability of patients through endometrial thickness, blood perfusion and other indicators.
Flow and method of IVF test
The procedures and methods of IVF examination may vary according to the specific conditions of different hospitals and patients. The following is a typical IVF examination process:
1. Preoperative evaluation and consultation
Patients usually need preoperative evaluation and consultation before deciding to perform IVF test. The doctor will know the patient's medical history, genetic background and birth history in detail to determine the most suitable examination items and treatment plan, and answer the patient's questions about IVF examination.
2. Inspection preparation
Before the specific IVF test, patients need to carry out a series of preparations for the test. This includes patients' genetic disease screening, hormone testing, endometrial testing, etc. According to the characteristics of the examination items, patients may need to take hormone drugs in a specific cycle, receive ultrasonic examination or endometrial puncture and other operations.
3. Check operation
According to the specific test tube baby test items, doctors will collect eggs from the patient's ovary or conduct gene testing on the embryo in the laboratory. Ovarian oocyte collection is usually conducted by ultrasound guided transvaginal puncture to extract the eggs from the follicles. Embryo gene detection is usually performed by separating the cytoplasm and nucleus of the embryo through the technology of nuclear cytoplasmic aspiration, and then performing gene detection.
4. Result evaluation and treatment
The evaluation of IVF test results is mainly to determine the next treatment plan according to the patient's specific conditions and test results. According to different examination items and results, doctors may recommend patients to carry out embryo transfer, assisted reproductive technology treatment or further genetic counseling.
Summary
The types of items involved in IVF mainly include embryo gene testing, preimplantation genetic diagnosis, genetic disease screening, hormone testing and endometrial testing. Through these inspection items, we can evaluate the genetic status and fertility conditions of IVF embryos and patients, and provide personalized treatment programs for patients. The procedures and methods of IVF examination mainly include preoperative evaluation and consultation, examination preparation, examination operation, result evaluation and treatment. The specific examination items and operation methods need to be adjusted and determined according to the patient's situation. The goal of IVF test is to help patients get pregnant successfully and reduce the risk of transmission of genetic diseases.
