Improving the success rate of embryo transfer test tube babies
Embryo transfer is an assisted reproductive technology, which aims to help couples who cannot conceive naturally realize their fertility aspirations. However, due to the complexity and uncertainty of embryo transfer, the success rate is relatively low. In order to improve the success rate of embryo transfer test tube babies, we can improve from the following aspects:
Optimize embryo culture environment
The birth of IVF is closely related to the development of embryo. Optimizing the embryo culture environment can provide more suitable growth conditions and increase the survival and development ability of embryos. First of all, it is necessary to ensure the quality and stability of the culture medium to ensure that the embryo can obtain sufficient nutrition and energy. Secondly, the environmental parameters such as oxygen concentration, temperature and humidity can be precisely controlled with the help of advanced incubator and cultivation technology. Finally, we can try to use biomaterials, cytokines and other auxiliary factors to improve the growth environment of embryos.
For example, Shanghai Ailihua Reproductive Hospital has introduced self-developed culture media in embryo culture and precisely controlled the culture environment parameters, which has successfully improved the success rate of IVF for embryo transfer.
Screening high-quality embryos
The quality of embryos determines the success rate of embryo transfer. In order to improve the success rate, embryo screening technology can be introduced to select high-quality embryos for transplantation. A common screening method is embryo chromosome karyotype screening. By detecting the number and structure of embryo chromosomes, embryos with normal chromosomes are screened for transplantation. In addition, embryo quality assessment indicators, such as cell division speed, cell morphology and cytoplasmic uniformity, can also be used to comprehensively assess the development status and quality of embryos.
Hangzhou Union Medical College Gynecology Hospital has established an embryo screening laboratory and introduced embryo chromosome karyotype screening technology. Through screening high-quality embryos, the success rate of embryo transfer in vitro babies has been greatly improved.
Rational drug treatment
Drug therapy plays a key role in the process of embryo transfer. Reasonable drug treatment can promote ovarian ovulation and control the state of endometrium, and improve the success rate of embryo transfer. First, the chance of successful fertilization can be increased by stimulating ovarian ovulation with ovulation promoting drugs. Secondly, appropriately customized hormone replacement therapy can maintain the appropriate thickness and status of endometrium and provide a good environment for embryo implantation.
Precision transplantation technology
Transfer technology is the core of embryo transfer. One of the keys to improve the success rate of embryo transfer is to use accurate transfer technology. First, make sure that the time of embryo transfer matches the state of endometrium. Secondly, navigation technology can be used to assist operation to improve the accuracy and stability of transplantation. In addition, after transplantation, strengthening accurate observation and management, and adjusting the treatment plan in time will also help to improve the success rate of transplantation.
To sum up, in order to improve the success rate of IVF embryo transfer, we can start from optimizing the embryo culture environment, screening high-quality embryos, rational drug treatment and precision transfer technology. Through continuous improvement and innovation, we hope to realize their childbearing dreams for more couples.
