How can the success rate of IVF infants at 40 years old be improved?
The development of IVF technology has enabled many infertile couples to achieve their reproductive aspirations. However, with the growth of age, the success rate of IVF has gradually decreased, especially for women aged 40. In order to improve the success rate of IVF infants at the age of 40, the following aspects can be improved.
1. Optimize the treatment plan
When treating 40 year old women with IVF, it is necessary to develop personalized treatment plans. First, doctors need to fully understand the patient's physical condition and reproductive system function to determine the most appropriate drug dosage and treatment cycle. At the same time, in view of the decline in egg quality of 40 year old women, we can consider increasing the number of eggs and adopting the method of polycystic follicle stimulation to improve the access rate of fertilized eggs.
Secondly, reasonable embryo transfer strategy is also the key to success. According to the patient's condition, single or multiple embryo transfers, as well as the best combination of age and embryo quality, can be selected to maximize the implantation rate.
In addition, considering that 40 year old women may have other basic diseases, such as hypertension and diabetes, active management and treatment of these diseases will help to improve the success rate of IVF.
2. Improve fertilization technology
In IVF treatment, fertilization is a crucial link. For 40 year old women, due to the decline of egg quality, more advanced fertilization technologies can be considered, such as microinjection sperm injection (ICSI) and parthenogenetic embryo transfer (PN integrity assessment), to improve fertilization rate and embryo quality.
ICSI technology can directly inject a sperm into an egg, which solves the problem of egg fertilization ability and improves the fertilization rate. PN integrity assessment technology can assess the fertilization ability and development potential of embryos, select the most promising embryos for transplantation, and reduce the risk of implantation failure.
3. Introduction of auxiliary technology
In addition to the traditional IVF technology, the introduction of assistive technology is also a way to improve the success rate of 40 year old IVF babies. For example, progesterone replacement therapy can be used to improve the thickness and quality of endometrium and increase the chances of embryo implantation. In addition, according to the patient's condition, we can also consider using embryo chromosome screening technology to exclude the transfer of embryos with chromosome abnormalities, and improve the implantation and pregnancy rate.
4. Psychological support and adjustment
40 year old IVF patients may face great psychological pressure and anxiety, and a good psychological state is essential to improve the success rate. The hospital can provide psychological support and counseling services to help patients alleviate anxiety and pressure and maintain a positive attitude. In addition, the support of patients' families and the society can not be ignored, which can provide emotional support and encouragement for patients.
To sum up, in order to improve the success rate of 40 year old IVF infants, we can improve the treatment plan, improve fertilization technology, introduce assistive technology and psychological support and adjustment. The comprehensive application of these measures is expected to effectively improve the success rate of IVF and help more women over 40 realize their reproductive dreams.
