Possible problems indicated by abnormal HCG values in test tube infants
In Vitro Fertilization (IVF) is an assisted reproductive technology, which helps couples who cannot conceive naturally realize their dreams of fertility by cultivating the fertilized eggs in vitro and successfully implanting them into the mother's body. During IVF, one of the important indicators to measure the implantation of embryos and whether the mother is successful in pregnancy is the content of human chorionic gonadotropin (HCG).
1. Early pregnancy
In the success rate of IVF, abnormal HCG value can often indicate early pregnancy problems. Normally, after the fertilized egg is implanted, the embryo begins to secrete HCG. If the HCG content is abnormally low, it may mean that the implantation of the fertilized egg is not ideal, which can be a sign of difficult implantation or implantation failure.
On the other hand, if the HCG content is abnormally high, it may mean multiple pregnancy. Multiple pregnancy increases the risk of various complications, such as premature delivery, placental dysfunction, etc. Therefore, the abnormal HCG value may need further inspection and monitoring to determine the pregnancy situation and develop appropriate intervention measures.
2. Abnormal embryonic development
Abnormal HCG values may also indicate problems in embryonic development. Under normal circumstances, the content of HCG will increase rapidly in the first trimester of pregnancy and gradually decrease in the next few weeks. Abnormally low HCG value may indicate slow or stagnant embryonic development, which may lead to embryo implantation failure or pregnancy abortion.
On the other hand, abnormally high HCG value may mean abnormal embryonic development, such as embryonic chromosome abnormalities (such as Down syndrome), atypical pregnancy (such as ectopic pregnancy) or other embryonic development problems. These problems may lead to pregnancy failure or pregnancy complications.
3. Human intervention
During IVF, doctors and patients may need to give HCG injection to promote follicle rupture and ovulation. However, if the HCG injection is used excessively or the concentration of the injection is abnormally high, the HCG value will rise abnormally.
High HCG value may lead to luteal insufficiency, ovarian hyperstimulation syndrome and other problems, and then affect the implantation of fertilized eggs and the development of embryos. Therefore, during IVF, doctors need to carefully monitor and control the use of HCG to avoid the impact of human factors on HCG values.
4. Metabolic problems
The abnormal HCG value may also be related to metabolic problems. In some cases, abnormally high HCG values may be caused by metabolic diseases such as diabetes, hyperthyroidism, etc. These diseases may affect the implantation of fertilized eggs and the development of embryos, thus leading to the failure of IVF.
In conclusion, the abnormal HCG value of IVF may indicate early pregnancy problems, abnormal embryonic development, human intervention problems and metabolic problems. Therefore, by monitoring the content of HCG value, doctors can find and deal with such problems as soon as possible, so as to improve the success rate of IVF and reduce complications.
