Reasons for the low success rate of IVF
Test tube baby is an assisted reproductive technology, which aims to help couples who cannot conceive naturally achieve their reproductive aspirations. However, due to various factors, the success rate of IVF is relatively low. The following will discuss the reasons for the low success rate of IVF from the aspects of embryo quality, endometrial environment, patient age and medical technology.
Embryo quality
Embryo quality is one of the important factors affecting the success rate of IVF. In the process of in vitro fertilization, due to changes in the environment and the constraints of culture conditions, some fertilized eggs have abnormal development or chromosome abnormalities. These problems will lead to the decrease of embryo quality, implantation and survival rate. In addition, due to the lack of natural selection mechanism of embryos, unhealthy embryos may continue to develop into fetuses, but cannot be successfully conceived.
In order to improve embryo quality, some hospitals have adopted embryo detection technologies, such as PGS (Preimplantation Genetic Screening). This technology can detect chromosomal abnormalities in embryos, improve the probability of selecting healthy embryos, and thus improve the success rate of IVF.
Endometrial environment
Endometrial environment is also one of the important factors affecting the success rate of IVF. The intimal environment includes intimal thickness, blood flow perfusion and intimal state. If the intima is too thin or the blood flow is insufficient, the embryo is easy to fail to implant and develop. In addition, the instability of the endometrial state will also affect the implantation ability of the embryo. The influence of some diseases or operations, such as hysteromyoma, endometriosis, etc., may lead to poor endometrial environment, and thus affect the success rate of IVF.
In order to improve the endometrial environment, some hospitals will prepare and adjust the endometrium. Through hormone therapy, the status and thickness of endometrium can be adjusted, the blood flow perfusion of endometrium can be increased, and the success rate of embryo implantation can be improved.
Patient's age
The patient's age is also one of the important factors affecting the success rate of IVF. The quality of female eggs gradually decreases with age, and the number of eggs also decreases. This means that the success rate of fertilization and embryo development will be significantly reduced for older women during IVF. The sperm quality of men will also decline with the increase of age, thus reducing the fertility.
In order to improve the success rate of IVF for older patients, some hospitals use auxiliary technologies, such as egg donation and embryo transfer. The pregnancy rate of IVF can be improved by using young and healthy eggs or embryos.
Medical technology
The limitation of medical technology is also one of the reasons for the low success rate of IVF. Despite the rapid development of IVF technology, it still faces some technical problems. For example, there are still many challenges in the selection of implantation site, optimization of culture environment, and embryo detection before embryo implantation.
In order to improve the level of medical technology, some hospitals have strengthened their scientific research and constantly explored new technologies and methods. For example, artificial intelligence technology is applied to optimize embryo selection and implantation site selection to improve the success rate of IVF.
conclusion
The low success rate of IVF is mainly affected by multiple factors such as embryo quality, endometrial environment, patient age and medical technology. In order to improve the success rate of IVF, doctors and researchers continue to explore new technologies and methods, such as embryo detection, endometrial regulation and egg donation. With the progress of science and technology and the improvement of medical level, it is believed that the success rate of IVF will gradually increase.
