Is the success rate of IVF related to age?
IVF technology is a way to help couples who are difficult to conceive naturally realize their dreams of childbirth. However, many people have doubts about whether the success rate of IVF is related to age. This paper will discuss this issue from different perspectives.
Measurement index
First, to examine the success rate of IVF, we need to know some measurement indicators. Common indicators include clinical pregnancy rate and live birth rate. Clinical pregnancy rate refers to the percentage of successful pregnancy of patients and the development of embryos in the uterus as the main basis. Live birth rate refers to the percentage of live births successfully delivered by IVF technology in the treatment group. These indicators will help us to analyze the relationship between the success rate of IVF and age.
One of the influencing factors: female age
Female age is one of the important factors affecting the success rate of IVF. According to the data from several clinical studies, the success rate of IVF is declining with the growth of women's age. This is because the ovarian function of women will decline with age, and the quality and quantity of eggs will also decrease. Therefore, for women over 30 years old, pregnancy will be more difficult. Especially for women over 40, the success rate is lower.
In addition to the decline of ovarian function, female age also has an impact on endometrial and ovarian response. Age will lead to the decrease of endometrial thickness and insufficient blood supply, which will have a negative impact on embryo implantation. In addition, the sensitivity of the ovary to ovulation promoting drugs will also be weakened, reducing the chance of successful pregnancy.
Influencing factor 2: male age
In addition to female age, male age also has an impact on the success rate of IVF. Early studies believed that male age had little relationship with the success rate of IVF, but recent studies have shown that male age does have an impact on the success rate of IVF. A study found that the clinical pregnancy rate of men over 35 years of age in the artificial insemination cycle of their spouses was significantly lower than that of men younger.
The aging of men may lead to the decline of sperm quality, including abnormal sperm morphology and decreased sperm concentration. This will directly affect the success rate of fertilization and embryo development. Therefore, it is suggested that men should also pay attention to the influence of age on the success rate of IVF, and carry out examination and treatment as soon as possible.
Influential factor 3: IVF technology
In addition to age, the success rate of IVF is also related to the technology itself. Factors such as selective embryo transfer, embryo culture, hormone therapy and so on will affect the success rate of IVF. With the progress of technology and the development of reproductive medicine, the success rate of IVF has gradually increased.
For example, a study found that for women over 40 years old, the hypoxic environment culture technology adopted by the Inoyama Research Institute of Osaka Medical University in Japan showed better results. In addition, customized hormone therapy and accurate embryo transfer time can also improve the success rate.
summary
In conclusion, the success rate of IVF is closely related to age. The growth of female age will lead to the decline of egg quality and quantity, the change of endometrium and the decline of ovarian response to hormones, thus affecting the success rate of IVF. Male age also has an impact on sperm quality, which in turn affects the success rate of fertilization and embryo development. In addition, the improvement of IVF technology also provides hope for more couples to realize their reproductive dreams. In the future, with the progress of science and technology, it is believed that the success rate of IVF technology will continue to improve.
