How is the malformation rate of test tube babies calculated?

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How is the malformation rate of IVF calculated?

With the development of IVF technology, many infertile couples have the opportunity to realize their reproductive dreams. However, with the increase of the number of IVF, people pay more attention to the safety and deformity rate of IVF. So, how to calculate the malformation rate of IVF?

Background: Definition and process of IVF

In vitro fertilization (IVF) refers to the technology of transferring fertilized eggs into the mother's uterus to develop into babies under the conditions of in vitro fertilization and embryo culture. The whole process includes egg collection, combination of sperm and egg, embryo culture and transplantation. The high risk of IVF technology has led to concerns about its deformity rate.

Method of calculating deformity rate

The malformation rate of IVF is usually calculated through actual observation and retrospective study. Here are some common calculation methods.

1. Practical observation method

The practical observation method refers to the long-term tracking of the born IVF babies to record whether there are various abnormalities. This method collects and analyzes the actual data to get the true deformity rate.

Take a real hospital as an example. Since 2000, the hospital has implemented IVF technology, and observed and recorded the malformations of all born IVF babies. After years of practice, the hospital has obtained a deformity rate data based on actual observation.

2. Review research method

The retrospective study method calculates the malformation rate by reviewing the data of IVF in the past. The researcher will check the records of the early embryonic development stage and the relevant documents of the mother's pregnancy, and then evaluate whether there is any abnormality in the IVF.

For example, the researchers selected a group of women who had IVF in a hospital and collected their personal information, embryo transfer records and relevant data during pregnancy. By reviewing these data, researchers can infer the malformation rate of this batch of IVF babies.

3. Comparative research method

Comparative studies often compare the malformation rate of IVF with that of naturally conceived infants. This approach can help to assess the impact of IVF technology on the risk of malformations.

In a comparative study, the researchers compared the IVF group and the natural pregnancy group to analyze the abnormalities of the two groups of infants. By comparing the two groups of data, we can speculate whether the malformation rate of IVF is higher than that of naturally conceived infants.

epilogue

The calculation methods of IVF malformation rate include actual observation, retrospective study and comparative study. These methods help us evaluate the safety of IVF technology by collecting and analyzing actual data. However, it should be noted that different studies may draw different conclusions, and the level of malformation rate may be affected by many factors, such as mother's age, basic diseases, etc. Therefore, when choosing IVF technology, prospective parents should take their own conditions into consideration and fully consult and communicate with professional doctors.