How to judge the embryo quality of IVF
Test tube baby is an important achievement of colonization technology. Its success depends largely on the quality of embryos. How to judge embryo quality has become the focus of scientists and doctors. Now, we will elaborate on the judgment methods of embryo quality from four aspects: embryo morphology, genetic testing, development speed and cytoplasmic evaluation.
Embryonic morphology
The appearance characteristics of embryos can provide a lot of information about their health and development potential. Generally speaking, round, symmetrical embryos without obvious malformations are usually of good quality, with higher survival rate and successful pregnancy rate. After years of experience, professional doctors and laboratory staff can preliminarily judge the quality of embryos by observing the morphological characteristics of embryos, such as cell number, adhesion, membrane transparency, etc.
In addition, taking and recording images during embryonic development is also a common assessment method. By observing the cell division and differentiation of the embryo and evaluating the integrity and stability of its development, we can judge the quality of the embryo more accurately.
Genetic testing
Genetic testing is one of the important means to evaluate embryo quality. Through genome analysis of embryos, embryos carrying certain genetic disease genes can be screened to avoid the transfer of these embryos and reduce the risk of disease. At the same time, genetic testing can also evaluate the chromosome normality of embryos, and exclude the risk of embryo malformation and spontaneous abortion caused by chromosome abnormalities.
At present, common genetic testing methods include: in vitro fertilization embryo suspension (PGS) and genetic single nucleotide polymorphism (PDG). These techniques can provide important genetic information before embryo transfer, help doctors judge the quality of embryos, and improve the success rate of pregnancy.
Growth rate
The rate of embryo development is another important indicator for evaluating embryo quality. Generally, the cell division and development of the embryo should be regular and orderly. The speed of cell division is too fast or too slow, which may mean that there are some problems in the embryo, such as chromosome abnormalities or embryonic development defects.
According to international standards, embryos generally need to go through a development process of 5 to 6 days from fertilization to maturity. Doctors and laboratory staff will divide embryos into different development stages according to the division of embryonic cells. If the development speed and stage of the embryo are consistent with the normal embryo, it means that the quality of the embryo is better and it is more suitable for transplantation.
Cytoplasmic evaluation
Cytoplasmic assessment is a method to directly observe the structure and function of embryo cells. By detecting the morphology, distribution and activity of various organelles and functional substances in the cytoplasm, the metabolic capacity, physiological status and development potential of the embryo can be evaluated.
At present, cytoplasmic evaluation mainly relies on microscopic observation and biochemical technology. Among them, laser confocal microscopy and staining technology can provide high-resolution images of embryonic cytoplasm to help doctors judge whether organelles are normal and cell metabolism is normal.
Summary
The embryo quality of IVF can be judged by embryo morphology, genetic testing, growth rate and cytoplasmic evaluation. The appearance characteristics, genetic test results, development speed and cytoplasmic structure of embryos are all important indicators for evaluating embryo quality. Accurate evaluation of embryo quality can not only improve the success rate of IVF, but also reduce the risk of disease and ensure the health of infants.
