Implantation rate of IVF and its influencing factors
IVF technology is an assisted reproductive technology, which increases the chance of successful pregnancy by culturing the fertilized eggs in vitro and selecting the best embryo for implantation. The implantation rate of IVF refers to the ratio of successful adhesion and development of embryos after implantation, which affects the chance of IVF successful pregnancy. The implantation rate is affected by many factors, which will be described in detail from the following aspects.
1. Age
Female age has a greater impact on IVF implantation rate. The aging of women will lead to the decline of ovarian function and egg quality, thus reducing the implantation rate. According to statistics, the implantation rate of women under 30 years old is about 40% - 50%, 30% - 40% between 30 and 35 years old, and 10% - 20% over 35 years old. In addition, the evaluation of female ovarian reserve function is also of great significance to the bed rate. For women with low ovarian response, the implantation rate is lower.
Male age also has some influence on IVF implantation rate. The aging of men will lead to the decline of sperm quality, which will affect the quality of embryos and implantation rate. Some studies have shown that the implantation rate of IVF will be significantly reduced when men are over 60 years old.
2. Body weight and body mass index (BMI)
Body weight and BMI also have some influence on the implantation rate of IVF. Overweight or obese women are often accompanied by hormone secretion disorders, abnormal ovulation, endometrial abnormalities and other problems, which will reduce the implantation rate. On the other hand, women who are underweight also tend to have difficulty in implantation due to lack of adequate fat reserves.
In addition, research shows that the weight and BMI of men are also related to the implantation rate of IVF. The quality and quantity of sperm carried by overweight or obese men may be affected, thus affecting embryonic development and implantation rate.
3. Endometrial status
The state of endometrium has an important influence on the implantation rate of IVF. The thickness and quality of endometrium play a key role in embryo implantation. Thin or poor quality intima is difficult to provide adequate nutrition and support, thus affecting the development and adhesion of embryos. Endometriosis also affects the implantation rate of IVF.
4. Preovulation promotion process
The early ovulation promotion process of IVF technology, such as the selection of ovulation promoting agents, dosage and design of medication scheme, will also affect the implantation rate of IVF. Excessive drug dosage may lead to the disorder of intrauterine environment, poor embryonic development, and thus reduce the implantation rate. Therefore, a reasonable and personalized ovulation induction program is essential to improve the implantation rate.
In conclusion, the implantation rate of IVF is affected by many factors. Age, body weight, BMI, endometrial status and ovulation induction in the early stage all have important effects on IVF implantation rate. Understanding these factors and taking corresponding control measures can help improve the implantation rate of IVF and increase the chance of successful pregnancy.
