What are the differences between the first generation and the second generation of IVF?

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Difference between the first generation and the second generation of IVF

Since the birth of IVF technology in the 1970s, it has experienced many technological innovations and developments. There are some significant differences between the first generation IVF technology and the current second generation IVF technology. This article will elaborate from four aspects: pregnancy rate, infant quality, multiple pregnancy and social cognition.

Pregnancy rate

The pregnancy rate of the first generation IVF technology is low, about 20%. This is because in this technology, only a small number of fertilized eggs can be transferred to the mother, and the probability of successful pregnancy is very limited. At the same time, the operation technology and equipment conditions of the first generation IVF technology are relatively backward, which can not effectively screen the best quality fertilized eggs, thus affecting the improvement of pregnancy rate. However, with the continuous development of IVF technology, the technical pregnancy rate of the second generation of IVF has significantly increased, reaching more than 40% to 50%. Thanks to the introduction of a new generation of technologies, including assisted incubation technology, embryo time dynamic observation technology and gene screening technology, doctors can better screen high-quality embryos for transfer to the mother, thus improving the success rate of pregnancy.

Infant quality

The quality of the first generation IVF infants is relatively poor. Due to the inability to accurately screen high-quality fertilized eggs, the birth weight of the first generation IVF babies is generally low, and the incidence of congenital diseases and genetic diseases is also high. This has brought certain health and economic burdens to children and families. In contrast, the second-generation IVF technology has greatly improved the quality of infants. Through gene screening and embryo time dynamic observation technology, doctors can screen healthy fertilized eggs and conduct comprehensive gene testing before transplantation, reducing the incidence of genetic diseases. At the same time, the application of assisted incubation technology also makes the birth weight of infants more balanced, reducing the incidence of low birth weight infants and premature infants.

Multiple pregnancy

The first generation of IVF technology is often accompanied by the problem of multiple pregnancy. Because multiple fertilized eggs need to be placed at the same time during the transfer process, the probability of multiple embryos developing at the same time and pregnancy success increases. However, multiple pregnancy has a great health risk, which affects both the mother and the fetus. The second generation of IVF technology has made significant progress in multiple pregnancy. Through the dynamic observation technology of embryo time, doctors can more accurately determine the best time for embryo transfer, and transfer the embryos that are most likely to develop into healthy fetuses, thus reducing the risk of multiple pregnancy.

social cognition

During the first generation of IVF technology, people had many doubts and prejudices about IVF. Many people held conservative attitudes towards IVF, even had malicious guesses. This is mainly due to the lack of popular science publicity and social cognition, leading to many people's misunderstanding of IVF. However, with the development of the second generation of IVF technology, people's understanding of IVF has gradually increased. Through the hospital's publicity and science popularization, people have a deeper understanding of IVF, and the acceptance and recognition of IVF has gradually improved. In summary, there are significant differences between the first generation IVF technology and the second generation IVF technology in pregnancy rate, infant quality, multiple pregnancy and social cognition. With the continuous development of IVF technology, the second generation IVF technology has made great progress in improving pregnancy rate and infant quality, reducing the risk of multiple pregnancies and improving social cognition, providing better choices for couples who cannot conceive naturally.