What are the indications of the 3rd generation IVF?
Generation 3 IVF technology (also known as embryo transfer technology) is an assisted reproductive technology, which is used to help couples who cannot conceive naturally achieve their reproductive aspirations. This technology has been widely used in the treatment of various infertility. The following will elaborate on the indications of the third-generation IVF from four aspects: genetic diseases, structural diseases, immune diseases and endocrine diseases.
Hereditary disease
Hereditary disease is a disease caused by gene mutation or defect. These diseases may have adverse effects on the development and health of embryos, or even lead to the early death of embryos. Through the 3-generation IVF technology, we can screen embryos with normal genes to avoid passing on genetic diseases to the next generation.
For example, blastocyst genetic diagnosis (PGD) is a commonly used 3-generation IVF technology to detect common genetic diseases, such as congenital heart disease, Down's syndrome and thalassemia. Hospitals such as Peking Union Medical College Hospital and Ruijin Hospital affiliated to Shanghai Jiaotong University School of Medicine can detect and treat PGD technology.
Structural disease
Structural diseases refer to diseases caused by abnormal embryonic or late embryonic development, which may affect the normal development of internal organs, limbs or head and other structures of infants. When one of the couples has structural diseases, or one or more children have structural diseases, they can choose to carry out 3-generation IVF technology to reduce the risk of disease in the next generation.
For example, the Affiliated Hospital of New York University provides structural disease screening services for third-generation IVF, such as screening for spina bifida, cleft lip and palate, and heart defects.
Immune diseases
Immune diseases are diseases caused by abnormal immune system, which may affect women's ability to conceive, leading to habitual abortion or infertility. In some special cases, such as some autoimmune diseases, antiphospholipid antibody syndrome and systemic lupus erythematosus, the use of third-generation IVF technology can help couples successfully conceive and give birth to healthy children.
For example, London Potzfarr Hospital is a hospital specializing in assisted reproduction of immune diseases, providing immune disease treatment services for third-generation test tube babies.
Endocrine diseases
Endocrine diseases refer to diseases caused by abnormal endocrine system functions, which may lead to the disorder of female hormone levels, and then have adverse effects on pregnancy and embryonic development. Some common endocrine diseases, such as polycystic ovary syndrome (PCOS) and hypothyroidism, can be assisted by third-generation IVF technology.
The Reproductive Medicine Center of Imperial College London School of Medicine has provided a treatment plan for three generations of test tube babies to treat infertility related to endocrine diseases.
summary
The 3rd generation IVF technology is an assisted reproductive technology, which is suitable for the treatment of various infertility, including genetic diseases, structural diseases, immune diseases and endocrine diseases. It provides a choice to help couples with fertility difficulties achieve their fertility aspirations, while reducing the risk of illness for the next generation. Many hospitals at home and abroad provide services of third-generation IVF technology to meet the needs of different couples.
