Background
IVF is a common method of assisted reproductive technology, which is used to help couples who cannot conceive naturally realize their reproductive dreams. However, the success rate of IVF is still limited, only about 30% of the attempts can be successful. In recent years, some studies have shown that immune regulation may help to improve the pregnancy rate of IVF. The following will discuss how to improve the pregnancy rate of IVF through immune regulation from different aspects.
Significance of immune regulation
The application of immune regulation in test tube babies means that by improving the function of the maternal immune system, reducing the immune response to the embryo, thereby improving the probability of pregnancy. Abnormal or over activation of maternal immune system may lead to spontaneous abortion or implantation failure of embryos. Therefore, immune regulation can adjust the response of the immune system and provide a more favorable environment for the success of IVF.
Specific immune regulation methods
In IVF, the methods of immune regulation mainly include the following aspects.
1. Application of immunosuppressants: Some studies have found that the use of immunosuppressants, such as prednisone, in the process of IVF can reduce the attack of maternal immune system on embryos. These immunosuppressants can increase the chances of embryo implantation by inhibiting the function of immune cells.
2. Application of immunomodulators: immunomodulators can adjust the function of the immune system and reduce the activity of immune cells. Some immunomodulatory drugs, such as antibodies that promote the activation of T cells and drugs that inhibit the activity of B cells, are widely used in the process of IVF to improve the probability of pregnancy.
3. Application of immune detection: The function of maternal immune system can be evaluated by analyzing the level of immune cells and related immune markers in maternal blood. Through immune detection, we can know whether there is an abnormal immune system in the mother and the specific ways to regulate it.
Application of immune regulation in actual hospitals
The application of immunomodulation in IVF has been applied in some hospitals. For example, XX Hospital recently carried out a study to improve the function of maternal immune system through the use of immunomodulators and immunosuppressants, which significantly improved the success rate of test tube babies. The hospital has incorporated immunomodulation into the routine operation of IVF, and individualized immunomodulation therapy is carried out according to the specific conditions of the mother.
In addition, XX Hospital has also widely used immune detection technology in clinical practice to provide a basis for the treatment of test tube babies by analyzing the immune function indicators of patients. The results of immune testing can help doctors understand the immune status of patients and select appropriate immune regulation methods, thus improving the pregnancy rate of IVF.
Summary
Immune regulation can improve the pregnancy rate of IVF. In practical application, the application of immunosuppressants and immunomodulators can reduce the attack of maternal immune system on embryos, thus increasing the chances of implantation. At the same time, the application of immune detection technology can help doctors evaluate the function of the maternal immune system and formulate individualized immunomodulation treatment plans. Although the application of immunomodulation in IVF needs further research and verification, the current research results have shown its potential and prospects.
