Selectable embryo screening techniques for 40 year old IVF infants
IVF is an assisted reproductive technology, which allows infertile couples to achieve fertility by artificially cultivating and implanting embryos. In the process of IVF, embryo screening technology plays a vital role. For 40 year old patients, embryo screening technology can help them choose healthy embryos, improve the success rate of pregnancy and the health status of the baby. The following will introduce in detail the optional embryo screening technologies for 40 year old IVF from four aspects: genetic disease screening, chromosome abnormality screening, gender screening and morphological screening.
Genetic disease screening
Hereditary diseases are diseases caused by abnormal genes or chromosome mutations. 40 year old IVF patients can exclude embryos with common or familial genetic disease genes through genetic disease screening technology when selecting embryos. These screening techniques include gene sequencing, multiple amplification reaction and Sanger sequencing. For example, some common genetic diseases such as cystic fibrosis, thalassemia and phenylketonuria can be screened through these technologies.
In addition, some professional IVF hospitals, such as Peking Union Medical College Hospital and Shanghai Tongji Hospital, provide genetic counseling services to help patients understand their own genetic risks and conduct genetic counseling.
Chromosome abnormality screening
Chromosome abnormality refers to the abnormality of chromosome structure or number, which may lead to pregnancy failure, abortion or birth defects. 40 year old IVF patients face a high risk of chromosomal abnormalities, which can be reduced through chromosomal abnormality screening technology. The most commonly used technique is terminal fragment site analysis (SNP-PCR), which can detect the number and structural abnormalities of chromosomes.
Chromosome abnormality screening technology is generally provided by professional laboratories such as the Reproductive Medicine Center of the PLA General Hospital or the Third Hospital of Peking University. These laboratories are equipped with advanced testing equipment and experienced professional teams, which can provide accurate screening results for patients.
Gender screening
Sex screening refers to the technology of determining the sex of embryos in the process of IVF. Although the use of gender screening is restricted in some countries, it is legal in some countries, such as the United States and Thailand. For some families, children of a specific gender may be their first choice. For 40 year old patients, gender screening can help them select embryos that meet their needs in the process of IVF.
Gender screening techniques include gene screening and embryo culture system screening. For example, through gene screening, the sex chromosome on the embryo can be detected (XX is female, XY is male). Embryo culture system screening is to predict the sex of embryos by evaluating their development in vitro.
Morphological screening
Morphological screening is to evaluate the health status of embryos by observing their morphology and structure. Normal embryos should have clear cell structure and symmetrical morphological characteristics. When 40 year old IVF patients select embryos, morphological screening can help them select embryos with good health.
Morphological screening is usually performed by embryology experts in IVF hospitals. These experts judge the health status of embryos by microscopic observation and evaluation of their appearance characteristics. Morphological screening can help patients select the most promising embryos to develop into healthy fetuses.
summary
Selectable embryo screening technologies for test tube infants at the age of 40 include genetic disease screening, chromosome abnormality screening, gender screening and morphological screening. Genetic disease screening can exclude embryos carrying common genetic disease genes. Chromosome abnormality screening can reduce the risk of chromosomal abnormalities. Gender screening can help families select embryos of a specific gender, while morphological screening can help select embryos that are most promising to develop into healthy fetuses. During embryo screening, patients can choose some well-known IVF hospitals, such as Peking Union Medical College Hospital and Shanghai Tongji Hospital, to obtain professional consultation and screening services.
